Basic Information Experimental Physicochemical Property Pharmacokinetic/Toxicokinetic Property Maximum Dosage Drug Property Radar Chart

Basic Information

Drug ID DDPD07565 ...
Drug Name Chloramphenicol succinate
Molecular Weight 423.202
Molecular Formula C15H16Cl2N2O8
CAS Number 3544-94-3
SMILES O[C@@H]([C@@H](COC(=O)CCC(O)=O)NC(=O)C(Cl)Cl)C1=CC=C(C=C1)[N+]([O-])=O
External Links
DRUGBANK DB07565
PubChem Compound 656580

Experimental Physicochemical Property

Not Available

Pharmacokinetic/ Toxicokinetic Property

Property Name Property Value Unit Raw Value Raw Unit Annotation Reference
C Max 11210.0 ng/ml 11.21±3.42 ug/ml DRUGBANK
T Max 1.7 h 0.3-3 h DRUGBANK
T Max 1.0 h 1 h DRUGBANK
Clearance 32.1 L/h 530-540 ml/min Total clearance; normal renal function; normal hepatic function; patients; DRUGBANK
Clearance 21.2 L/h 354.0 ml/min Total clearance; RD, renal impairment, Renal disease，including uremia; hepatopathy，LD; patients; DRUGBANK
Clearance 14.5 L/h 222-260 ml/min Renal clearance; normal renal function; normal hepatic function; patients; DRUGBANK
Clearance 4.0 L/h 66.0 ml/min Renal clearance; RD, renal impairment, Renal disease，including uremia; hepatopathy，LD; patients; DRUGBANK
Volume of Distribution 1.7 L/kg 0.2-3.1 L/kg DRUGBANK
Half-life 1.7 h 0.6-2.7 h normal renal function; normal hepatic function; patients; DRUGBANK
Eliminate Route 30.0 % 30(6-80) % Urinary excretion; Unchanged drug; DRUGBANK
Protein Binding 74.5 % 57-92 % plasma proteins; DRUGBANK

Maximum Dosage

Not Available

Drug Property Radar Chart

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Note: Center: Q1-1.5*IQR, Edge: Q3+1.5*IQR; Q1: Quantile 1, Q3: Quantile 3, IQR: Q3-Q1