Basic Information
Experimental Physicochemical Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Reference |
|---|---|---|---|---|---|
| Boiling Point | 266.0 | ℃ | 266 | ℃ | MSDS |
| Melting Point | 12.0 | ℃ | 12 | ℃ | MSDS |
Pharmacokinetic/ Toxicokinetic Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Annotation | Reference |
|---|---|---|---|---|---|---|
| Bioavailability | 19.0 | % | 8-30 | % | PO, oral; | DRUGBANK |
| T Max | 2.4 | h | 0.8-4 | h | PO, oral; | DRUGBANK |
| Volume of Distribution | 393.0 | L | 393.0 | L | Total volume of distribution; | DRUGBANK | Volume of Distribution | 252.0 | L | 252.0 | L | Total volume of distribution; | DRUGBANK |
| Half-life | 2.7 | h | 1.3-4 | h | elimination half-life; normal,healthy; | DRUGBANK | Half-life | 2.7 | h | 1.3-4 | h | elimination half-life; Wilson's disease; patients; | DRUGBANK |
| Toxicity LD50 | 2500.0 | mg/kg | 2500.0 | mg/kg | PO, oral; Rattus, Rat; | DRUGBANK | Toxicity LD50 | 1600.0 | mg/kg | 1600.0 | mg/kg | PO, oral; mouse; | DRUGBANK | Toxicity LD50 | 5500.0 | mg/kg | 5500.0 | mg/kg | PO, oral; rabbit; | DRUGBANK |
Maximum Dosage
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Annotation | Brand Name | Component | Reference |
|---|---|---|---|---|---|---|---|---|
| Max dose for children | 1500.0 | mg/day | 1500 | mg/day | PO, oral | Syprine | trientine hydrochloride | PDR |
| Max dose for adolescents | 2000.0 | mg/day | 2000 | mg/day | PO, oral | Syprine | trientine hydrochloride | PDR |
| Max dose for adults | 2000.0 | mg/day | 2000 | mg/day | PO, oral | Syprine | trientine hydrochloride | PDR |
| Max dose for elderly | 2000.0 | mg/day | 2000 | mg/day | PO, oral | Syprine | trientine hydrochloride | PDR |
Drug Property Radar Chart
Note: Center: Q1-1.5*IQR, Edge: Q3+1.5*IQR; Q1: Quantile 1, Q3: Quantile 3, IQR: Q3-Q1