Basic Information
| Drug ID | DDPD06819 |
|
| Drug Name | Phenylbutyric acid | |
| Molecular Weight | 164.2011 | |
| Molecular Formula | C10H12O2 | |
| CAS Number | 1821-12-1 | |
| SMILES | OC(=O)CCCC1=CC=CC=C1 | |
| External Links | ||
| DRUGBANK | DB06819 | |
| PubChem Compound | 4775 | |
| PDR | 1782 | |
| Drugs.com | Drugs.com Drug Page | |
Experimental Physicochemical Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Reference |
|---|---|---|---|---|---|
| Melting Point | 150.0 | ℃ | >150 | ℃ | MSDS |
| Water Solubility | 100.0 | mg/L | 100 | mM | MSDS |
Pharmacokinetic/ Toxicokinetic Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Annotation | Reference |
|---|---|---|---|---|---|---|
| C Max | 218000.0 | ng/ml | 218 | mcg/ml | Tablet, PO, oral; fasting; | DRUGBANK | C Max | 195000.0 | ng/ml | 195 | mcg/ml | PO, oral; fasting; | DRUGBANK |
| Volume of Distribution | 0.21 | L/kg | 0.21 | L/kg | DRUGBANK | |
| Half-life | 0.77 | h | 0.77 | h | DRUGBANK | Half-life | 1.2 | h | 1.15 | h | DRUGBANK |
Maximum Dosage
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Annotation | Brand Name | Component | Reference |
|---|---|---|---|---|---|---|---|---|
| Max dose for neonates | 20000.0 | mg/day | 20 | g/day | Buphenyl | sodium phenylbutyrate | PDR | |
| Max dose for infants | 20.0 | g/day | 20 | g/day | Buphenyl | sodium phenylbutyrate | PDR | |
| Max dose for children | 20000.0 | mg/day | 20 | g/day | Buphenyl | sodium phenylbutyrate | PDR | |
| Max dose for adolescents | 20000.0 | mg/day | 20 | g/day | Buphenyl | sodium phenylbutyrate | PDR | |
| Max dose for adults | 20000.0 | mg/day | 20 | g/day | Buphenyl | sodium phenylbutyrate | PDR | |
| Max dose for geriatric | 20000.0 | mg/day | 20 | g/day | Buphenyl | sodium phenylbutyrate | PDR |
Drug Property Radar Chart
Note: Center: Q1-1.5*IQR, Edge: Q3+1.5*IQR; Q1: Quantile 1, Q3: Quantile 3, IQR: Q3-Q1