Basic Information
| Drug ID | DDPD06817 |
|
| Drug Name | Raltegravir | |
| Molecular Weight | 444.4163 | |
| Molecular Formula | C20H21FN6O5 | |
| CAS Number | 518048-05-0 | |
| SMILES | CN1C(=O)C(O)=C(N=C1C(C)(C)NC(=O)C1=NN=C(C)O1)C(=O)NCC1=CC=C(F)C=C1 | |
| External Links | ||
| DRUGBANK | DB06817 | |
| PubChem Compound | 54671008 | |
| PDR | 360 | |
| Drugs.com | Drugs.com Drug Page | |
Experimental Physicochemical Property
Not Available
Pharmacokinetic/ Toxicokinetic Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Annotation | Reference |
|---|---|---|---|---|---|---|
| Half-life | 9.0 | h | 9 | h | DRUGBANK | |
| Protein Binding | 83.0 | % | 83 | % | DRUGBANK |
Maximum Dosage
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Annotation | Brand Name | Component | Reference |
|---|---|---|---|---|---|---|---|---|
| Max dose for neonates | 30.0 | mg/day | 30 | mg/day | Liquid | Isentress | raltegravir | PDR |
| Max dose for neonates | 20.0 | mg/day | 20 | mg/day | Liquid | Isentress | raltegravir | PDR |
| Max dose for neonates | 16.0 | mg/day | 16 | mg/day | Liquid | Isentress | raltegravir | PDR |
| Max dose for neonates | 7.0 | mg/day | 7 | mg/day | Liquid | Isentress | raltegravir | PDR |
| Max dose for neonates | 5.0 | mg/day | 5 | mg/day | Liquid | Isentress | raltegravir | PDR |
| Max dose for neonates | 4.0 | mg/day | 4 | mg/day | Liquid | Isentress | raltegravir | PDR |
| Max dose for infants | 160.0 | mg/day | 160 | mg/day | Liquid | Isentress | raltegravir | PDR |
| Max dose for infants | 150.0 | mg/day | 150 | mg/day | Tablet,PO，oral | Isentress | raltegravir | PDR |
| Max dose for infants | 120.0 | mg/day | 120 | mg/day | Liquid | Isentress | raltegravir | PDR |
| Max dose for infants | 80.0 | mg/day | 80 | mg/day | Liquid | Isentress | raltegravir | PDR |
| Max dose for infants | 60.0 | mg/day | 60 | mg/day | Liquid | Isentress | raltegravir | PDR |
| Max dose for infants | 50.0 | mg/day | 50 | mg/day | Liquid | Isentress | raltegravir | PDR |
| Max dose for children | 600.0 | mg/day | 600 | mg/day | Tablet,PO，oral | Isentress | raltegravir | PDR |
| Max dose for children | 800.0 | mg/day | 800 | mg/day | Tablet,PO，oral | Isentress | raltegravir | PDR |
| Max dose for children | 1200.0 | mg/day | 1200 | mg/day | Tablet,PO，oral | Isentress | raltegravir | PDR |
| Max dose for children | 400.0 | mg/day | 400 | mg/day | Tablet,PO，oral | Isentress | raltegravir | PDR |
| Max dose for children | 800.0 | mg/day | 800 | mg/day | Tablet,PO，oral | Isentress | raltegravir | PDR |
| Max dose for children | 300.0 | mg/day | 300 | mg/day | Tablet,PO，oral | Isentress | raltegravir | PDR |
| Max dose for children | 800.0 | mg/day | 800 | mg/day | Tablet,PO，oral | Isentress | raltegravir | PDR |
| Max dose for children | 300.0 | mg/day | 300 | mg/day | Tablet,PO，oral | Isentress | raltegravir | PDR |
| Max dose for children | 200.0 | mg/day | 200 | mg/day | Tablet,PO，oral | Isentress | raltegravir | PDR |
| Max dose for children | 160.0 | mg/day | 160 | mg/day | Liquid | Isentress | raltegravir | PDR |
| Max dose for children | 150.0 | mg/day | 150 | mg/day | Tablet,PO，oral | Isentress | raltegravir | PDR |
| Max dose for children | 120.0 | mg/day | 120 | mg/day | Liquid | Isentress | raltegravir | PDR |
| Max dose for adolescents | 600.0 | mg/day | 600 | mg/day | PO, oral | Isentress | raltegravir | PDR |
| Max dose for adolescents | 800.0 | mg/day | 800 | mg/day | PO, oral | Isentress | raltegravir | PDR |
| Max dose for adolescents | 1200.0 | mg/day | 1200 | mg/day | PO, oral | Isentress | raltegravir | PDR |
| Max dose for adolescents | 400.0 | mg/day | 400 | mg/day | PO, oral | Isentress | raltegravir | PDR |
| Max dose for adolescents | 800.0 | mg/day | 800 | mg/day | PO, oral | Isentress | raltegravir | PDR |
| Max dose for adults | 800.0 | mg/day | 800 | mg/day | PO, oral | Isentress | raltegravir | PDR |
| Max dose for adults | 1600.0 | mg/day | 1600 | mg/day | PO, oral | Isentress | raltegravir | PDR |
| Max dose for adults | 1200.0 | mg/day | 1200 | mg/day | Isentress | raltegravir | PDR | |
| Max dose for geriatric | 800.0 | mg/day | 800 | mg/day | PO, oral | Isentress | raltegravir | PDR |
| Max dose for geriatric | 1600.0 | mg/day | 1600 | mg/day | PO, oral | Isentress | raltegravir | PDR |
| Max dose for geriatric | 1200.0 | mg/day | 1200 | mg/day | Isentress | raltegravir | PDR |
Drug Property Radar Chart
Note: Center: Q1-1.5*IQR, Edge: Q3+1.5*IQR; Q1: Quantile 1, Q3: Quantile 3, IQR: Q3-Q1