Basic Information
| Drug ID | DDPD06811 |
|
| Drug Name | Polidocanol | |
| Molecular Weight | 582.8073 | |
| Molecular Formula | C30H62O10 | |
| CAS Number | 9002-92-0 | |
| SMILES | CCCCCCCCCCCCOCCOCCOCCOCCOCCOCCOCCOCCOCCO | |
| External Links | ||
| DRUGBANK | DB06811 | |
| PubChem Compound | 656641 | |
| PDR | 3411 | |
| Drugs.com | Drugs.com Drug Page | |
Experimental Physicochemical Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Reference |
|---|---|---|---|---|---|
| Log P | 3.94 | - | 3.94 | - | # http://www.chemicalize.org/structure/#!mol=polidocanol |
| Boiling Point | 615.857 | ℃ | 615.857 | ℃ | DRUGBANK |
| Melting Point | 34.5 | ℃ | 33-36 | ℃ | DRUGBANK |
Pharmacokinetic/ Toxicokinetic Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Annotation | Reference |
|---|---|---|---|---|---|---|
| T Max | 0.25 | h | 15 | min | DRUGBANK | |
| Clearance | 18.0 | L/h | 0.2-0.4 | L/min | Total clearance; | DRUGBANK |
| Volume of Distribution | 58.5 | L | 35-82 | L | intravenous injection, IV; | DRUGBANK |
| Half-life | 1.5 | h | ~1.5 | h | DRUGBANK |
Maximum Dosage
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Annotation | Brand Name | Component | Reference |
|---|---|---|---|---|---|---|---|---|
| Max dose for adults | 5.0 | ml/dose | 5 | ml/dose | Varithena | polidocanol | PDR | |
| Max dose for adults | 15.0 | ml/session | 15 | ml/session | Varithena | polidocanol | PDR | |
| Max dose for adults | 0.3 | ml/dose | 0.3 | ml/dose | Varithena | polidocanol | PDR | |
| Max dose for adults | 10.0 | ml/session | 10 | ml/session | Varithena | polidocanol | PDR | |
| Max dose for geriatric | 5.0 | ml/dose | 5 | ml/dose | Varithena | polidocanol | PDR | |
| Max dose for geriatric | 15.0 | ml/session | 15 | ml/session | Varithena | polidocanol | PDR | |
| Max dose for geriatric | 0.3 | ml/dose | 0.3 | ml/dose | Varithena | polidocanol | PDR | |
| Max dose for geriatric | 10.0 | ml/session | 10 | ml/session | Varithena | polidocanol | PDR |
Drug Property Radar Chart
Note: Center: Q1-1.5*IQR, Edge: Q3+1.5*IQR; Q1: Quantile 1, Q3: Quantile 3, IQR: Q3-Q1