Basic Information
| Drug ID | DDPD06802 |
|
| Drug Name | Nepafenac | |
| Molecular Weight | 254.2839 | |
| Molecular Formula | C15H14N2O2 | |
| CAS Number | 78281-72-8 | |
| SMILES | NC(=O)CC1=CC=CC(C(=O)C2=CC=CC=C2)=C1N | |
| External Links | ||
| DRUGBANK | DB06802 | |
| PubChem Compound | 151075 | |
| PDR | 3041 | |
| Drugs.com | Drugs.com Drug Page | |
Experimental Physicochemical Property
Not Available
Pharmacokinetic/ Toxicokinetic Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Annotation | Reference |
|---|---|---|---|---|---|---|
| Eliminate Route | 85.0 | % | ~85 | % | Urinary excretion; PO, oral; normal,healthy; human, homo sapiens; | DRUGBANK | Eliminate Route | 6.0 | % | ~6 | % | Faeces excretion; PO, oral; normal,healthy; human, homo sapiens; | DRUGBANK |
| Protein Binding | 95.4 | % | 95.4 | % | high protein binding; human, homo sapiens; | DRUGBANK | Protein Binding | 99.1 | % | 99.1 | % | high protein binding; human, homo sapiens; | DRUGBANK |
Maximum Dosage
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Annotation | Brand Name | Component | Reference |
|---|---|---|---|---|---|---|---|---|
| Max dose for children | 3.0 | drop/day | 3 | drop/day | ophthalmic administration | Ilevro | nepafenac | PDR |
| Max dose for children | 1.0 | drop/day | 1 | drop/day | ophthalmic administration | Ilevro | nepafenac | PDR |
| Max dose for adolescents | 3.0 | drop/day | 3 | drop/day | ophthalmic administration | Ilevro | nepafenac | PDR |
| Max dose for adolescents | 1.0 | drop/day | 1 | drop/day | ophthalmic administration | Ilevro | nepafenac | PDR |
| Max dose for adults | 3.0 | drop/day | 3 | drop/day | ophthalmic administration | Ilevro | nepafenac | PDR |
| Max dose for adults | 1.0 | drop/day | 1 | drop/day | ophthalmic administration | Ilevro | nepafenac | PDR |
| Max dose for geriatric | 3.0 | drop/day | 3 | drop/day | ophthalmic administration | Ilevro | nepafenac | PDR |
| Max dose for geriatric | 1.0 | drop/day | 1 | drop/day | ophthalmic administration | Ilevro | nepafenac | PDR |
Drug Property Radar Chart
Note: Center: Q1-1.5*IQR, Edge: Q3+1.5*IQR; Q1: Quantile 1, Q3: Quantile 3, IQR: Q3-Q1