Basic Information Experimental Physicochemical Property Pharmacokinetic/Toxicokinetic Property Maximum Dosage Drug Property Radar Chart

Basic Information

Drug ID DDPD06796 ...
Drug Name Mangafodipir
Molecular Weight 691.382
Molecular Formula C22H30MnN4O14P2
CAS Number 155319-91-8
SMILES [Mn++].CC1=C(O)C(CN(CCN(CC([O-])=O)CC2=CC(COP(O)(O)=O)=NC(C)=C2O)CC([O-])=O)=CC(COP(O)(O)=O)=N1
External Links
DRUGBANK DB06796
PubChem Compound 131704299

Experimental Physicochemical Property

Not Available

Pharmacokinetic/ Toxicokinetic Property

Property Name Property Value Unit Raw Value Raw Unit Annotation Reference
Clearance 0.19 L/h/kg ~3.1 ml/min/kg Total clearance; dog; DRUGBANK
Volume of Distribution 1.0 L/kg 0.5-1.5 L/kg DRUGBANK
Half-life 0.33 h ~20 min distribution half-life; DRUGBANK
Half-life 0.83 h 50 min DRUGBANK
Toxicity LD50 3456.9 mg/kg 5.0 mmol/kg mouse; DRUGBANK
Eliminate Route 17.5 % ~15-20 % Urinary excretion; DRUGBANK
Protein Binding 27.0 % ~27 % DRUGBANK

Maximum Dosage

Not Available

Drug Property Radar Chart

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Note: Center: Q1-1.5*IQR, Edge: Q3+1.5*IQR; Q1: Quantile 1, Q3: Quantile 3, IQR: Q3-Q1