Basic Information Experimental Physicochemical Property Pharmacokinetic/Toxicokinetic Property Maximum Dosage Drug Property Radar Chart

Basic Information

Drug ID DDPD06789 ...
Drug Name Hydroxyprogesterone caproate
Molecular Weight 428.6041
Molecular Formula C27H40O4
CAS Number 630-56-8
SMILES [H][C@@]12CC[C@](OC(=O)CCCCC)(C(C)=O)[C@@]1(C)CC[C@@]1([H])[C@@]2([H])CCC2=CC(=O)CC[C@]12C
External Links
DRUGBANK DB06789
PubChem Compound 169870
PDR 1409
Drugs.com Drugs.com Drug Page

Experimental Physicochemical Property

Property Name Property Value Unit Raw Value Raw Unit Reference
Melting Point 120.0 ℃ 119-121 ℃ U.S. Patent 2,753,360.

Pharmacokinetic/ Toxicokinetic Property

Property Name Property Value Unit Raw Value Raw Unit Annotation Reference
Half-life 384.0 h 16±6 day DRUGBANK
Eliminate Route 50.0 % ~50 % Faeces excretion; IM,intramuscular injection; DRUGBANK
Eliminate Route 30.0 % ~30 % Urinary excretion; IM,intramuscular injection; DRUGBANK

Maximum Dosage

Property Name Property Value Unit Raw Value Raw Unit Annotation Frequency Brand Name Component Reference
Max dose for adolescents 5.10204081632653 mg/day 250 mg/week IM,intramuscular injection qw Makena hydroxyprogesterone caproate PDR
Max dose for adolescents 5.61224489795918 mg/day 275 mg/week subcutaneous injection, SC qw Makena hydroxyprogesterone caproate PDR
Max dose for adolescents 375.0 mg/dose 375 mg/dose IM,intramuscular injection Makena hydroxyprogesterone caproate PDR
Max dose for adolescents 375.0 mg/dose 375 mg/dose IM,intramuscular injection Makena hydroxyprogesterone caproate PDR
Max dose for adults 35.7142857142857 mg/day 250 mg/week IM,intramuscular injection qw Makena hydroxyprogesterone caproate PDR
Max dose for adults 39.2857142857143 mg/day 275 mg/week subcutaneous injection, SC qw Makena hydroxyprogesterone caproate PDR
Max dose for adults 375.0 mg/dose 375 mg/dose IM,intramuscular injection Makena hydroxyprogesterone caproate PDR
Max dose for adults 1000.0 mg/dose 1000 mg/dose IM,intramuscular injection Makena hydroxyprogesterone caproate PDR
Max dose for geriatric 375.0 mg/dose 375 mg/dose IM,intramuscular injection Makena hydroxyprogesterone caproate PDR
Max dose for geriatric 1000.0 mg/dose 1000 mg/dose IM,intramuscular injection Makena hydroxyprogesterone caproate PDR

Drug Property Radar Chart

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Note: Center: Q1-1.5*IQR, Edge: Q3+1.5*IQR; Q1: Quantile 1, Q3: Quantile 3, IQR: Q3-Q1