Basic Information
| Drug ID | DDPD06771 |
|
| Drug Name | Besifloxacin | |
| Molecular Weight | 393.84 | |
| Molecular Formula | C19H21ClFN3O3 | |
| CAS Number | 141388-76-3 | |
| SMILES | N[C@@H]1CCCCN(C1)C1=C(F)C=C2C(=O)C(=CN(C3CC3)C2=C1Cl)C(O)=O | |
| External Links | ||
| DRUGBANK | DB06771 | |
| PubChem Compound | 10178705 | |
| PDR | 68 | |
| Drugs.com | Drugs.com Drug Page | |
Experimental Physicochemical Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Reference |
|---|---|---|---|---|---|
| pKa | 6.5 | - | 6.0-7.0 | - | MSDS |
Pharmacokinetic/ Toxicokinetic Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Annotation | Reference |
|---|---|---|---|---|---|---|
| Metabolic | 0 | % | ~0 | % | DRUGBANK | |
| Half-life | 7.0 | h | 7 | h | elimination half-life; Multiple dose; | DRUGBANK |
| Toxicity LD50 | 2000.0 | mg/kg | >2000 | mg/kg | Rattus, Rat; | DRUGBANK |
Maximum Dosage
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Annotation | Brand Name | Component | Reference |
|---|---|---|---|---|---|---|---|---|
| Max dose for children | 3.0 | drop/day | 3 | drop/day | ophthalmic administration | Besivance | besifloxacin | PDR |
| Max dose for adolescents | 3.0 | drop/day | 3 | drop/day | ophthalmic administration | Besivance | besifloxacin | PDR |
| Max dose for adults | 3.0 | drop/day | 3 | drop/day | ophthalmic administration | Besivance | besifloxacin | PDR |
| Max dose for elderly | 3.0 | drop/day | 3 | drop/day | ophthalmic administration | Besivance | besifloxacin | PDR |
Drug Property Radar Chart
Note: Center: Q1-1.5*IQR, Edge: Q3+1.5*IQR; Q1: Quantile 1, Q3: Quantile 3, IQR: Q3-Q1