Basic Information
| Drug ID | DDPD06766 |
|
| Drug Name | Alcaftadine | |
| Molecular Weight | 307.3895 | |
| Molecular Formula | C19H21N3O | |
| CAS Number | 147084-10-4 | |
| SMILES | CN1CCC(CC1)=C1C2=NC=C(C=O)N2CCC2=CC=CC=C12 | |
| External Links | ||
| DRUGBANK | DB06766 | |
| PubChem Compound | 19371515 | |
| PDR | 1377 | |
| Drugs.com | Drugs.com Drug Page | |
Experimental Physicochemical Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Reference |
|---|---|---|---|---|---|
| Log P | 3.202 | - | 3.202 | - | # http://www.lookchem.com/Product_842767/CasNo_147084-10-4/Alcaftadine.html#.UXtC3Ct5N_k |
| Boiling Point | 556.247 | ℃ | 556.247 | ℃ | # http://www.lookchem.com/Product_842767/CasNo_147084-10-4/Alcaftadine.html#.UXtC3Ct5N_k |
Pharmacokinetic/ Toxicokinetic Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Annotation | Reference |
|---|---|---|---|---|---|---|
| Half-life | 2.0 | h | 2 | h | elimination half-life; skin/dermal; | DRUGBANK |
| Protein Binding | 39.2 | % | 39.2 | % | DRUGBANK |
Maximum Dosage
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Annotation | Frequency | Brand Name | Component | Reference |
|---|---|---|---|---|---|---|---|---|---|
| Max dose for children | 1.0 | drop/day | 1 | drop/day | ophthalmic administration | qd | Lastacaft | alcaftadine | PDR |
| Max dose for adolescents | 1.0 | drop/day | 1 | drop/day | ophthalmic administration | qd | Lastacaft | alcaftadine | PDR |
| Max dose for adults | 1.0 | drop/day | 1 | drop/day | ophthalmic administration | qd | Lastacaft | alcaftadine | PDR |
| Max dose for geriatric | 1.0 | drop/day | 1 | drop/day | ophthalmic administration | qd | Lastacaft | alcaftadine | PDR |
Drug Property Radar Chart
Note: Center: Q1-1.5*IQR, Edge: Q3+1.5*IQR; Q1: Quantile 1, Q3: Quantile 3, IQR: Q3-Q1