Basic Information Experimental Physicochemical Property Pharmacokinetic/Toxicokinetic Property Maximum Dosage Drug Property Radar Chart

Basic Information

Drug ID DDPD06704 ...
Drug Name Iobenguane
Molecular Weight 275.0896
Molecular Formula C8H10IN3
CAS Number 80663-95-2
SMILES NC(N)=NCC1=CC(I)=CC=C1
External Links
DRUGBANK DB06704
PubChem Compound 60860
PDR 24229
Drugs.com Drugs.com Drug Page

Experimental Physicochemical Property

Property Name Property Value Unit Raw Value Raw Unit Reference
Boiling Point 100.0 ℃ 100 ℃ MSDS
Melting Point 0.0 ℃ 0 ℃ MSDS

Pharmacokinetic/ Toxicokinetic Property

Property Name Property Value Unit Raw Value Raw Unit Annotation Reference
Metabolic 10.0 % <10 % DRUGBANK
Half-life 13.2 h 13.2 h physical half-life; DRUGBANK
Toxicity LD50 300.0 mg/kg 300.0 mg/kg PO, oral; mouse; DRUGBANK
Toxicity LD50 3200.0 mg/kg 3200.0 mg/kg PO, oral; rabbit; DRUGBANK
Toxicity LD50 980.0 mg/kg 980.0 mg/kg PO, oral; Rattus, Rat; DRUGBANK
Eliminate Route 1.0 % <1 % Faeces excretion; DRUGBANK

Maximum Dosage

Property Name Property Value Unit Raw Value Raw Unit Annotation Brand Name Component Reference
Max dose for children 296.0 MBq/kg 296 MBq/kg intravenous injection, IV Azedra iobenguane I 131 PDR
Max dose for children 8.0 mCi/kg 8 mCi/kg intravenous injection, IV Azedra iobenguane I 131 PDR
Max dose for adolescents 18500.0 MBq 18500 MBq intravenous injection, IV Azedra iobenguane I 131 PDR
Max dose for adolescents 500.0 mCi 500 mCi intravenous injection, IV Azedra iobenguane I 131 PDR
Max dose for adolescents 296.0 MBq/kg 296 MBq/kg intravenous injection, IV Azedra iobenguane I 131 PDR
Max dose for adolescents 8.0 mCi/kg 8 mCi/kg intravenous injection, IV Azedra iobenguane I 131 PDR
Max dose for adults 18500.0 MBq 18500 MBq intravenous injection, IV Azedra iobenguane I 131 PDR
Max dose for adults 500.0 mCi 500 mCi intravenous injection, IV Azedra iobenguane I 131 PDR
Max dose for adults 296.0 MBq/kg 296 MBq/kg intravenous injection, IV Azedra iobenguane I 131 PDR
Max dose for adults 8.0 mCi/kg 8 mCi/kg intravenous injection, IV Azedra iobenguane I 131 PDR
Max dose for geriatric 18500.0 MBq 18500 MBq intravenous injection, IV Azedra iobenguane I 131 PDR
Max dose for geriatric 500.0 mCi 500 mCi intravenous injection, IV Azedra iobenguane I 131 PDR
Max dose for geriatric 296.0 MBq/kg 296 MBq/kg intravenous injection, IV Azedra iobenguane I 131 PDR
Max dose for geriatric 8.0 mCi/kg 8 mCi/kg intravenous injection, IV Azedra iobenguane I 131 PDR

Drug Property Radar Chart

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Note: Center: Q1-1.5*IQR, Edge: Q3+1.5*IQR; Q1: Quantile 1, Q3: Quantile 3, IQR: Q3-Q1