| Property Name |
Property Value |
Unit |
Raw Value |
Raw Unit |
Annotation |
Factor |
Reference |
| Bioavailability |
80.0 |
% |
80 |
% |
PO, oral; food; |
food → ; |
DRUGBANK |
| T Max |
7.5 |
h |
7.5 |
h |
PO, oral; |
|
DRUGBANK |
| Clearance |
0.29 |
L/h/kg |
4.9 |
ml/min/kg |
intravenous injection, IV; human, homo sapiens; |
|
Human Intravenous Pharmacokinetic Dataset |
| Volume of Distribution |
3.4 |
L/kg |
3.4 |
L/kg |
|
|
DRUGBANK |
Volume of Distribution |
3.5 |
L/kg |
3.5 |
L/kg |
intravenous injection, IV; human, homo sapiens; |
|
Human Intravenous Pharmacokinetic Dataset |
| Half-life |
11.1 |
h |
11.1 |
h |
terminal half-life; |
moderate hepatic impairment ↑ ;severe hepatic impairment ↑ ;moderate renal function ↑ ;severe renal function ↑ ; |
DRUGBANK |
Half-life |
8.4 |
h |
8.4 |
h |
intravenous injection, IV; human, homo sapiens; |
|
Human Intravenous Pharmacokinetic Dataset |
| Eliminate Route |
45.0 |
% |
45 |
% |
Urinary excretion; Unchanged drug; |
|
DRUGBANK |
| Protein Binding |
30.0 |
% |
30 |
% |
|
Plasma Concentration → ; |
DRUGBANK |
