Basic Information
| Drug ID | DDPD06697 |
|
| Drug Name | Artemether | |
| Molecular Weight | 298.3746 | |
| Molecular Formula | C16H26O5 | |
| CAS Number | 71963-77-4 | |
| SMILES | [H][C@@]12CC[C@@H](C)[C@]3([H])CC[C@@]4(C)OO[C@@]13[C@]([H])(O[C@H](OC)[C@@H]2C)O4 | |
| External Links | ||
| DRUGBANK | DB06697 | |
| PubChem Compound | 68911 | |
| Drugs.com | Drugs.com Drug Page | |
Experimental Physicochemical Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Reference |
|---|---|---|---|---|---|
| Log P | 3.53 | - | 3.53 | - | AVERY,MA ET AL. (1995) |
| Melting Point | 88.0 | ℃ | 86-90 | ℃ | DRUGBANK |
Pharmacokinetic/ Toxicokinetic Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Annotation | Reference |
|---|---|---|---|---|---|---|
| Half-life | 1.6 | h | 1.6±0.7 | h | distribution half-life; | DRUGBANK | Half-life | 2.2 | h | 2.2±1.9 | h | elimination half-life; | DRUGBANK | Half-life | 1.6 | h | 1.6±0.6 | h | distribution half-life; | DRUGBANK | Half-life | 2.2 | h | 2.2±1.5 | h | elimination half-life; | DRUGBANK |
| Toxicity LD50 | 895.0 | mg/kg | 895.0 | mg/kg | mouse; | DRUGBANK | Toxicity LD50 | 296.0 | mg/kg | 296.0 | mg/kg | mouse; | DRUGBANK | Toxicity LD50 | 597.0 | mg/kg | 597.0 | mg/kg | Rattus, Rat; | DRUGBANK |
| Protein Binding | 95.4 | % | 95.4 | % | human, homo sapiens; | DRUGBANK |
Maximum Dosage
Not Available
Drug Property Radar Chart
Note: Center: Q1-1.5*IQR, Edge: Q3+1.5*IQR; Q1: Quantile 1, Q3: Quantile 3, IQR: Q3-Q1