| Property Name |
Property Value |
Unit |
Raw Value |
Raw Unit |
Annotation |
Reference |
| Bioavailability |
72.0 |
% |
72 |
% |
PO, oral; food; |
DRUGBANK |
| Clearance |
22.5 |
L/h |
19.9-25.1 |
L/h |
mild renal function; moderate renal function; |
DRUGBANK |
Clearance |
26.7 |
L/h |
26.4-26.9 |
L/h |
normal,healthy; |
DRUGBANK |
Clearance |
0.23 |
L/h/kg |
3.76 |
ml/min/kg |
intravenous injection, IV; human, homo sapiens; |
Human Intravenous Pharmacokinetic Dataset |
| Volume of Distribution |
4.9 |
L/kg |
4.85 |
L/kg |
intravenous injection, IV; human, homo sapiens; |
Human Intravenous Pharmacokinetic Dataset |
| Half-life |
25.0 |
h |
25 |
h |
|
DRUGBANK |
Half-life |
24.0 |
h |
24±5.2 |
h |
Single dose; |
DRUGBANK |
Half-life |
28.9 |
h |
28.9±3.2 |
h |
Multiple dose; |
DRUGBANK |
Half-life |
15.7 |
h |
15.66 |
h |
intravenous injection, IV; human, homo sapiens; |
Human Intravenous Pharmacokinetic Dataset |
| Eliminate Route |
1.0 |
% |
1 |
% |
Urinary excretion; Unchanged drug; |
DRUGBANK |
Eliminate Route |
2.0 |
% |
2 |
% |
Faeces excretion; Unchanged drug; |
DRUGBANK |
| Protein Binding |
97.5 |
% |
96-99 |
% |
|
DRUGBANK |
