Basic Information
| Drug ID | DDPD06603 |
|
| Drug Name | Panobinostat | |
| Molecular Weight | 349.434 | |
| Molecular Formula | C21H23N3O2 | |
| CAS Number | 404950-80-7 | |
| SMILES | CC1=C(CCNCC2=CC=C(\C=C\C(=O)NO)C=C2)C2=CC=CC=C2N1 | |
| External Links | ||
| DRUGBANK | DB06603 | |
| PubChem Compound | 6918837 | |
| PDR | 3686 | |
| Drugs.com | Drugs.com Drug Page | |
Experimental Physicochemical Property
Not Available
Pharmacokinetic/ Toxicokinetic Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Annotation | Reference |
|---|---|---|---|---|---|---|
| T Max | 2.0 | h | 2 | h | DRUGBANK | |
| Metabolic | 2.0 | % | 2 | % | Urinary excretion; | DRUGBANK | Metabolic | 3.0 | % | 3 | % | Faeces excretion; | DRUGBANK |
| Clearance | 0.61 | L/h/kg | 10.2 | ml/min/kg | intravenous injection, IV; human, homo sapiens; | Human Intravenous Pharmacokinetic Dataset |
| Half-life | 30.0 | h | 30 | h | DRUGBANK | Half-life | 13.1 | h | 13.1 | h | intravenous injection, IV; human, homo sapiens; | Human Intravenous Pharmacokinetic Dataset |
Maximum Dosage
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Annotation | Brand Name | Component | Reference |
|---|---|---|---|---|---|---|---|---|
| Max dose for adults | 20.0 | mg/dose | 20 | mg/dose | PO, oral | Farydak | panobinostat | PDR |
| Max dose for adults | 10.0 | mg/dose | 10 | mg/dose | PO, oral | Farydak | panobinostat | PDR |
| Max dose for geriatric | 20.0 | mg/dose | 20 | mg/dose | PO, oral | Farydak | panobinostat | PDR |
| Max dose for geriatric | 10.0 | mg/dose | 10 | mg/dose | PO, oral | Farydak | panobinostat | PDR |
Drug Property Radar Chart
Note: Center: Q1-1.5*IQR, Edge: Q3+1.5*IQR; Q1: Quantile 1, Q3: Quantile 3, IQR: Q3-Q1