Basic Information

Drug ID DDPD06594 ...
Drug Name Agomelatine
Molecular Weight 243.301
Molecular Formula C15H17NO2
CAS Number 138112-76-2
SMILES COC1=CC2=C(C=CC=C2CCNC(C)=O)C=C1
External Links
DRUGBANK DB06594
PubChem Compound 82148

Experimental Physicochemical Property

Property Name Property Value Unit Raw Value Raw Unit Reference
Water Solubility 500.0 mg/L ~0.5 mg/ml in 1:1 EtOH:PBS (pH 7.2) mg/ml DRUGBANK
Water Solubility 30000.0 mg/L ~30 mg/ml in EtOH, DMF & DMSO mg/ml DRUGBANK

Pharmacokinetic/ Toxicokinetic Property

Property Name Property Value Unit Raw Value Raw Unit Annotation Reference
Bioavailability 5.0 % <5 % DRUGBANK
Metabolic 90.0 % 90 % Liver metabolism; DRUGBANK
Metabolic 10.0 % 10 % Liver metabolism; DRUGBANK
Half-life 2.0 h <2 h DRUGBANK
Protein Binding 95.0 % >95 % DRUGBANK

Maximum Dosage

Not Available

Drug Property Radar Chart

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Note: Center: Q1-1.5*IQR, Edge: Q3+1.5*IQR; Q1: Quantile 1, Q3: Quantile 3, IQR: Q3-Q1