Basic Information
| Drug ID | DDPD06414 |
|
| Drug Name | Etravirine | |
| Molecular Weight | 435.277 | |
| Molecular Formula | C20H15BrN6O | |
| CAS Number | 269055-15-4 | |
| SMILES | CC1=CC(=CC(C)=C1OC1=C(Br)C(N)=NC(NC2=CC=C(C=C2)C#N)=N1)C#N | |
| External Links | ||
| DRUGBANK | DB06414 | |
| PubChem Compound | 193962 | |
| PDR | 1241 | |
| Drugs.com | Drugs.com Drug Page | |
Experimental Physicochemical Property
Not Available
Pharmacokinetic/ Toxicokinetic Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Annotation | Reference |
|---|---|---|---|---|---|---|
| Half-life | 25.0 | h | 9.05-41 | h | DRUGBANK | |
| Eliminate Route | 93.7 | % | 93.7 | % | Faeces excretion; | DRUGBANK | Eliminate Route | 1.2 | % | 1.2 | % | Urinary excretion; | DRUGBANK |
| Protein Binding | 99.9 | % | 99.9 | % | plasma proteins; high protein binding; | DRUGBANK | Protein Binding | 99.6 | % | 99.6 | % | high protein binding; | DRUGBANK | Protein Binding | 98.3 | % | 97.66-99.02 | % | high protein binding; | DRUGBANK |
Maximum Dosage
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Annotation | Brand Name | Component | Reference |
|---|---|---|---|---|---|---|---|---|
| Max dose for children | 400.0 | mg/day | 400 | mg/day | PO, oral | Intelence | etravirine | PDR |
| Max dose for children | 300.0 | mg/day | 300 | mg/day | PO, oral | Intelence | etravirine | PDR |
| Max dose for children | 250.0 | mg/day | 250 | mg/day | PO, oral | Intelence | etravirine | PDR |
| Max dose for children | 200.0 | mg/day | 200 | mg/day | PO, oral | Intelence | etravirine | PDR |
| Max dose for adolescents | 400.0 | mg/day | 400 | mg/day | PO, oral | Intelence | etravirine | PDR |
| Max dose for adolescents | 300.0 | mg/day | 300 | mg/day | PO, oral | Intelence | etravirine | PDR |
| Max dose for adults | 400.0 | mg/day | 400 | mg/day | PO, oral | Intelence | etravirine | PDR |
| Max dose for geriatric | 400.0 | mg/day | 400 | mg/day | PO, oral | Intelence | etravirine | PDR |
Drug Property Radar Chart
Note: Center: Q1-1.5*IQR, Edge: Q3+1.5*IQR; Q1: Quantile 1, Q3: Quantile 3, IQR: Q3-Q1