Basic Information
| Drug ID | DDPD06413 |
|
| Drug Name | Armodafinil | |
| Molecular Weight | 273.35 | |
| Molecular Formula | C15H15NO2S | |
| CAS Number | 112111-43-0 | |
| SMILES | NC(=O)C[S@@](=O)C(C1=CC=CC=C1)C1=CC=CC=C1 | |
| External Links | ||
| DRUGBANK | DB06413 | |
| PubChem Compound | 9690109 | |
| PDR | 2335 | |
| Drugs.com | Drugs.com Drug Page | |
Experimental Physicochemical Property
Not Available
Pharmacokinetic/ Toxicokinetic Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Annotation | Reference |
|---|---|---|---|---|---|---|
| T Max | 2.0 | h | 2 | h | PO, oral; fasting; | DRUGBANK | T Max | 3.0 | h | 2-4 | h | PO, oral; food; | DRUGBANK |
| Clearance | 2.0 | L/h | ~33 | ml/min | PO, oral; | DRUGBANK |
| Volume of Distribution | 42.0 | L | 42.0 | L | Apparent volume of distribution; | DRUGBANK |
| Half-life | 15.0 | h | ~15 | h | terminal half-life; | DRUGBANK |
| Protein Binding | 60.0 | % | ~60 | % | DRUGBANK |
Maximum Dosage
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Annotation | Brand Name | Component | Reference |
|---|---|---|---|---|---|---|---|---|
| Max dose for adolescents | 250.0 | mg/day | 250 | mg/day | PO, oral | Nuvigil | armodafinil | PDR |
| Max dose for adolescents | 150.0 | mg/day | 150 | mg/day | PO, oral | Nuvigil | armodafinil | PDR |
| Max dose for adults | 250.0 | mg/day | 250 | mg/day | PO, oral | Nuvigil | armodafinil | PDR |
| Max dose for adults | 150.0 | mg/day | 150 | mg/day | PO, oral | Nuvigil | armodafinil | PDR |
| Max dose for geriatric | 250.0 | mg/day | 250 | mg/day | PO, oral | Nuvigil | armodafinil | PDR |
| Max dose for geriatric | 150.0 | mg/day | 150 | mg/day | PO, oral | Nuvigil | armodafinil | PDR |
Drug Property Radar Chart
Note: Center: Q1-1.5*IQR, Edge: Q3+1.5*IQR; Q1: Quantile 1, Q3: Quantile 3, IQR: Q3-Q1