| Property Name |
Property Value |
Unit |
Raw Value |
Raw Unit |
Annotation |
Reference |
| Bioavailability |
80.0 |
% |
>80 |
% |
PO, oral; |
DRUGBANK |
| T Max |
3.0 |
h |
2-4 |
h |
PO, oral; |
DRUGBANK |
| Clearance |
10.0 |
L/h |
10.0 |
L/h |
Total clearance; |
DRUGBANK |
Clearance |
3.5 |
L/h |
~3.0-4 |
L/h |
Renal clearance; |
DRUGBANK |
Clearance |
0.14 |
L/h/kg |
2.4 |
ml/min/kg |
intravenous injection, IV; human, homo sapiens; |
Human Intravenous Pharmacokinetic Dataset |
| Volume of Distribution |
50.0 |
L |
50.0 |
L |
Steady state volume of distribution; |
DRUGBANK |
Volume of Distribution |
0.70 |
L/kg |
0.7 |
L/kg |
intravenous injection, IV; human, homo sapiens; |
Human Intravenous Pharmacokinetic Dataset |
| Half-life |
7.0 |
h |
5-9 |
h |
terminal half-life; adults; |
DRUGBANK |
Half-life |
12.0 |
h |
11-13 |
h |
terminal half-life; Elderly; |
DRUGBANK |
Half-life |
7.0 |
h |
7 |
h |
intravenous injection, IV; human, homo sapiens; |
Human Intravenous Pharmacokinetic Dataset |
| Eliminate Route |
66.7 |
% |
~66.7 |
% |
Urinary excretion; |
DRUGBANK |
Eliminate Route |
33.3 |
% |
~33.3 |
% |
Faeces excretion; |
DRUGBANK |
Eliminate Route |
23.8 |
% |
23.76 |
% |
Urinary excretion; Unchanged drug; |
DRUGBANK |
Eliminate Route |
2.3 |
% |
2.3 |
% |
Faeces excretion; Unchanged drug; |
DRUGBANK |
| Protein Binding |
93.5 |
% |
92-95 |
% |
plasma proteins; |
DRUGBANK |
