Basic Information

Drug ID DDPD06217 ...
Drug Name Vernakalant
Molecular Weight 349.471
Molecular Formula C20H31NO4
CAS Number 794466-70-9
SMILES COC1=C(OC)C=C(CCO[C@@H]2CCCC[C@H]2N2CC[C@@H](O)C2)C=C1
External Links
DRUGBANK DB06217
PubChem Compound 9930049

Experimental Physicochemical Property

Not Available

Pharmacokinetic/ Toxicokinetic Property

Property Name Property Value Unit Raw Value Raw Unit Annotation Reference
C Max 3900.0 ng/ml 3.9 ug/ml patients; DRUGBANK
C Max 4300.0 ng/ml 4.3 ug/ml patients; DRUGBANK
Clearance 0.41 L/h/kg 0.41 l/h/kg Total clearance; DRUGBANK
Clearance 0.50 L/h/kg 8.29 ml/min/kg intravenous injection, IV; human, homo sapiens; Human Intravenous Pharmacokinetic Dataset
Volume of Distribution 2.0 L/kg ~2 L/kg DRUGBANK
Volume of Distribution 1.8 L/kg 1.8 L/kg intravenous injection, IV; human, homo sapiens; Human Intravenous Pharmacokinetic Dataset
Half-life 3.0 h 3 h elimination half-life; extensive metabolizers, EM; DRUGBANK
Half-life 5.5 h 5.5 h elimination half-life; poor metabolizers, PM; DRUGBANK
Half-life 3.1 h 3.13 h intravenous injection, IV; human, homo sapiens; Human Intravenous Pharmacokinetic Dataset

Maximum Dosage

Not Available

Drug Property Radar Chart

...

Note: Center: Q1-1.5*IQR, Edge: Q3+1.5*IQR; Q1: Quantile 1, Q3: Quantile 3, IQR: Q3-Q1