| Property Name |
Property Value |
Unit |
Raw Value |
Raw Unit |
Annotation |
Reference |
| C Max |
12.3 |
ng/ml |
12.3 |
ng/ml |
intravenous injection, IV; |
DRUGBANK |
| T Max |
0.0333 |
h |
1-3 |
min |
intravenous injection, IV; |
DRUGBANK |
| Clearance |
27.0 |
L/h |
450.0 |
ml/min |
Plasma clearance; Renal clearance; |
DRUGBANK |
Clearance |
0.44 |
L/h/kg |
7.3 |
ml/min/kg |
intravenous injection, IV; human, homo sapiens; |
Human Intravenous Pharmacokinetic Dataset |
| Volume of Distribution |
11.5 |
L |
11.5 |
L |
Total volume of distribution; |
DRUGBANK |
Volume of Distribution |
78.7 |
L |
78.7 |
L |
Steady state volume of distribution; |
DRUGBANK |
Volume of Distribution |
0.94 |
L/kg |
0.94 |
L/kg |
intravenous injection, IV; human, homo sapiens; |
Human Intravenous Pharmacokinetic Dataset |
| Half-life |
0.0500 |
h |
2-4 |
min |
distribution half-life; |
DRUGBANK |
Half-life |
0.50 |
h |
30 |
min |
elimination half-life; |
DRUGBANK |
Half-life |
2.0 |
h |
2 |
h |
terminal half-life; |
DRUGBANK |
Half-life |
2.0 |
h |
2 |
h |
intravenous injection, IV; human, homo sapiens; |
Human Intravenous Pharmacokinetic Dataset |
| Toxicity MTD |
0.0200 |
mg/kg |
20.0 |
ug/kg |
Male, men; |
DRUGBANK |
Toxicity MTD |
0.0100 |
mg/kg |
10.0 |
ug/kg |
Female, women; |
DRUGBANK |
| Eliminate Route |
58.0 |
% |
58 |
% |
Urinary excretion; |
DRUGBANK |
