Basic Information
| Drug ID | DDPD06209 |
|
| Drug Name | Prasugrel | |
| Molecular Weight | 373.441 | |
| Molecular Formula | C20H20FNO3S | |
| CAS Number | 150322-43-3 | |
| SMILES | CC(=O)OC1=CC2=C(CCN(C2)C(C(=O)C2CC2)C2=CC=CC=C2F)S1 | |
| External Links | ||
| DRUGBANK | DB06209 | |
| PubChem Compound | 6918456 | |
| PDR | 289 | |
| Drugs.com | Drugs.com Drug Page | |
Experimental Physicochemical Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Reference |
|---|---|---|---|---|---|
| Log P | 3.536 | - | 3.536 | - | MSDS |
Pharmacokinetic/ Toxicokinetic Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Annotation | Reference |
|---|---|---|---|---|---|---|
| Bioavailability | 79.0 | % | >79 | % | PO, oral; | DRUGBANK |
| T Max | 0.50 | h | 0.5 | h | PO, oral; | DRUGBANK | T Max | 1.0 | h | 0.5-1.5 | h | PO, oral; high-fat meal; | DRUGBANK |
| Clearance | 139.0 | L/h | 112-166 | L/h | apparent clearance; | DRUGBANK |
| Volume of Distribution | 56.0 | L | 44-68 | L | DRUGBANK | |
| Half-life | 7.4 | h | ~7.4(2-15) | h | elimination half-life; Active metabolite; | DRUGBANK |
| Toxicity LD50 | 1500.0 | mg/kg | 1000-2000 | mg/kg | Rattus, Rat; | DRUGBANK | Toxicity LD50 | 1000.0 | mg/kg | >1000 | mg/kg | rabbit; | DRUGBANK |
Maximum Dosage
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Annotation | Brand Name | Component | Reference |
|---|---|---|---|---|---|---|---|---|
| Max dose for adults | 10.0 | mg/day | 10 | mg/day | PO, oral | Effient | prasugrel | PDR |
| Max dose for adults | 60.0 | mg/dose | 60 | mg/dose | PO, oral | Effient | prasugrel | PDR |
| Max dose for elderly | 10.0 | mg/day | 10 | mg/day | PO, oral | Effient | prasugrel | PDR |
| Max dose for elderly | 60.0 | mg/dose | 60 | mg/dose | PO, oral | Effient | prasugrel | PDR |
| Max dose for elderly | 60.0 | mg/dose | 60 | mg/dose | PO, oral | Effient | prasugrel | PDR |
| Max dose for elderly | 10.0 | mg/day | 10 | mg/day | PO, oral | Effient | prasugrel | PDR |
Drug Property Radar Chart
Note: Center: Q1-1.5*IQR, Edge: Q3+1.5*IQR; Q1: Quantile 1, Q3: Quantile 3, IQR: Q3-Q1