| Property Name |
Property Value |
Unit |
Raw Value |
Raw Unit |
Annotation |
Reference |
| AUC |
373.0 |
ng.h/ml |
373.0 |
ng.h/ml |
PO, oral; food; |
DRUGBANK |
AUC |
1870.0 |
ng.h/ml |
1870.0 |
ng.h/ml |
PO, oral; food; Active metabolite; |
DRUGBANK |
| Bioavailability |
32.0 |
% |
32 |
% |
PO, oral; |
DRUGBANK |
| C Max |
61.6 |
ng/ml |
61.6±27.54 |
ng/ml |
PO, oral; food; |
DRUGBANK |
| T Max |
2.6 |
h |
2.6±0.90 |
h |
PO, oral; food; |
DRUGBANK |
| Clearance |
10.0 |
L/h |
10.0 |
L/h |
Plasma clearance; |
DRUGBANK |
Clearance |
0.17 |
L/h/kg |
2.8 |
ml/min/kg |
intravenous injection, IV; human, homo sapiens; |
Human Intravenous Pharmacokinetic Dataset |
| Volume of Distribution |
49.5 |
L |
49.5 |
L |
|
DRUGBANK |
| Half-life |
13.3 |
h |
13.3±8.07 |
h |
|
DRUGBANK |
Half-life |
24.0 |
h |
24 |
h |
Active metabolite; |
DRUGBANK |
Half-life |
3.6 |
h |
3.6 |
h |
intravenous injection, IV; human, homo sapiens; |
Human Intravenous Pharmacokinetic Dataset |
| Eliminate Route |
54.9 |
% |
54.9 |
% |
Faeces excretion; |
DRUGBANK |
Eliminate Route |
33.5 |
% |
33.5 |
% |
Urinary excretion; |
DRUGBANK |
| Protein Binding |
97.0 |
% |
97 |
% |
|
DRUGBANK |
