Basic Information
| Drug ID | DDPD06206 |
|
| Drug Name | Sugammadex | |
| Molecular Weight | 2002.12 | |
| Molecular Formula | C72H112O48S8 | |
| CAS Number | 343306-71-8 | |
| SMILES | O[C@@H]1[C@@H](O)[C@@H]2O[C@H]3O[C@H](CSCCC(O)=O)[C@@H](O[C@H]4O[C@H](CSCCC(O)=O)[C@@H](O[C@H]5O[C@H](CSCCC(O)=O)[C@@H](O[C@H]6O[C@H](CSCCC(O)=O)[C@@H](O[C@H]7O[C@H](CSCCC(O)=O)[C@@H](O[C@H]8O[C@H](CSCCC(O)=O)[C@@H](O[C@H]9O[C@H](CSCCC(O)=O)[C@@H](O[C@H]1O[C@@H]2CSCCC(O)=O)[C@H](O)[C@H]9O)[C@H](O)[C@H]8O)[C@H](O)[C@H]7O)[C@H](O)[C@H]6O)[C@H](O)[C@H]5O)[C@H](O)[C@H]4O)[C@H](O)[C@H]3O | |
| External Links | ||
| DRUGBANK | DB06206 | |
| PubChem Compound | 6918585 | |
| PDR | 3841 | |
Experimental Physicochemical Property
Not Available
Pharmacokinetic/ Toxicokinetic Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Annotation | Reference |
|---|---|---|---|---|---|---|
| Clearance | 5280.0 | L/h | 88.0 | L/min | DRUGBANK | Clearance | 0.0768 | L/h/kg | 1.28 | ml/min/kg | intravenous injection, IV; human, homo sapiens; | Human Intravenous Pharmacokinetic Dataset |
| Volume of Distribution | 12.5 | L | 11.0-14 | L | at steady state; normal renal function; patients; adults; | DRUGBANK | Volume of Distribution | 0.18 | L/kg | 0.18 | L/kg | intravenous injection, IV; human, homo sapiens; | Human Intravenous Pharmacokinetic Dataset |
| Half-life | 2.0 | h | ~2 | h | DRUGBANK | Half-life | 2.5 | h | 2.53 | h | intravenous injection, IV; human, homo sapiens; | Human Intravenous Pharmacokinetic Dataset |
| Eliminate Route | 90.0 | % | >90 | % | DRUGBANK | Eliminate Route | 0.0200 | % | 0.02 | % | Faeces excretion; | DRUGBANK |
| Protein Binding | 0 | % | 0 | % | plasma proteins; | DRUGBANK |
Maximum Dosage
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Annotation | Brand Name | Component | Reference |
|---|---|---|---|---|---|---|---|---|
| Max dose for adults | 16.0 | mg/kg | 16 | mg/kg | intravenous injection, IV | Bridion | sugammadex | PDR |
| Max dose for geriatric | 16.0 | mg/kg | 16 | mg/kg | intravenous injection, IV | Bridion | sugammadex | PDR |
Drug Property Radar Chart
Note: Center: Q1-1.5*IQR, Edge: Q3+1.5*IQR; Q1: Quantile 1, Q3: Quantile 3, IQR: Q3-Q1