Basic Information

Drug ID DDPD06193 ...
Drug Name Pixantrone
Molecular Weight 325.372
Molecular Formula C17H19N5O2
CAS Number 144510-96-3
SMILES NCCNC1=CC=C(NCCN)C2=C1C(=O)C1=C(C=NC=C1)C2=O
External Links
DRUGBANK DB06193
PubChem Compound 134019
Drugs.com Drugs.com Drug Page

Experimental Physicochemical Property

Not Available

Pharmacokinetic/ Toxicokinetic Property

Property Name Property Value Unit Raw Value Raw Unit Annotation Reference
Clearance 1.0 L/h/kg 0.75 - 1.31 l/h/kg Plasma clearance; DRUGBANK
Clearance 1.1 L/h/kg 17.7 ml/min/kg intravenous injection, IV; human, homo sapiens; Human Intravenous Pharmacokinetic Dataset
Volume of Distribution 19.7 L/kg 9.7-29.7 L/kg DRUGBANK
Volume of Distribution 10.1 L/kg 10.1 L/kg intravenous injection, IV; human, homo sapiens; Human Intravenous Pharmacokinetic Dataset
Half-life 12.0 h 12 h DRUGBANK
Half-life 13.4 h 13.4 h intravenous injection, IV; human, homo sapiens; Human Intravenous Pharmacokinetic Dataset
Eliminate Route 10.0 % <10 % Urinary excretion; Unchanged drug; DRUGBANK

Maximum Dosage

Not Available

Drug Property Radar Chart

...

Note: Center: Q1-1.5*IQR, Edge: Q3+1.5*IQR; Q1: Quantile 1, Q3: Quantile 3, IQR: Q3-Q1