Basic Information Experimental Physicochemical Property Pharmacokinetic/Toxicokinetic Property Maximum Dosage Drug Property Radar Chart

Basic Information

Drug ID DDPD06148 ...
Drug Name Mianserin
Molecular Weight 264.3648
Molecular Formula C18H20N2
CAS Number 24219-97-4
SMILES CN1CCN2C(C1)C1=CC=CC=C1CC1=CC=CC=C21
External Links
DRUGBANK DB06148
PubChem Compound 4184

Experimental Physicochemical Property

Not Available

Pharmacokinetic/ Toxicokinetic Property

Property Name Property Value Unit Raw Value Raw Unit Annotation Reference
Clearance 1.3 L/h/kg 21.9 ml/min/kg intravenous injection, IV; human, homo sapiens; Human Intravenous Pharmacokinetic Dataset
Volume of Distribution 13.8 L/kg 13.75 L/kg intravenous injection, IV; human, homo sapiens; Human Intravenous Pharmacokinetic Dataset
Half-life 13.5 h 10-17 h DRUGBANK
Half-life 9.6 h 9.6 h intravenous injection, IV; human, homo sapiens; Human Intravenous Pharmacokinetic Dataset
Toxicity LD50 780.0 mg/kg 780.0 mg/kg PO, oral; Rattus, Rat; DRUGBANK
Protein Binding 90.0 % 90 % DRUGBANK

Maximum Dosage

Not Available

Drug Property Radar Chart

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Note: Center: Q1-1.5*IQR, Edge: Q3+1.5*IQR; Q1: Quantile 1, Q3: Quantile 3, IQR: Q3-Q1