Basic Information
| Drug ID | DDPD06016 |
|
| Drug Name | Cariprazine | |
| Molecular Weight | 427.41 | |
| Molecular Formula | C21H32Cl2N4O | |
| CAS Number | 839712-12-8 | |
| SMILES | CN(C)C(=O)N[C@H]1CC[C@H](CCN2CCN(CC2)C2=C(Cl)C(Cl)=CC=C2)CC1 | |
| External Links | ||
| DRUGBANK | DB06016 | |
| PubChem Compound | 11154555 | |
| PDR | 3792 | |
| Drugs.com | Drugs.com Drug Page | |
Experimental Physicochemical Property
Not Available
Pharmacokinetic/ Toxicokinetic Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Annotation | Reference |
|---|---|---|---|---|---|---|
| Metabolic | 13.8 | % | 13.8 | % | Liver metabolism; | DRUGBANK | Metabolic | 12.3 | % | 12.3 | % | Liver metabolism; | DRUGBANK |
| Half-life | 168.0 | h | ~1 | week | Drug combination; | DRUGBANK |
| Eliminate Route | 21.0 | % | 21 | % | Urinary excretion; | DRUGBANK |
| Protein Binding | 94.0 | % | 91-97 | % | DRUGBANK |
Maximum Dosage
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Annotation | Brand Name | Component | Reference |
|---|---|---|---|---|---|---|---|---|
| Max dose for adults | 6.0 | mg/day | 6 | mg/day | PO, oral | Vraylar | cariprazine | PDR |
| Max dose for adults | 3.0 | mg/day | 3 | mg/day | PO, oral | Vraylar | cariprazine | PDR |
| Max dose for geriatric | 6.0 | mg/day | 6 | mg/day | PO, oral | Vraylar | cariprazine | PDR |
| Max dose for geriatric | 3.0 | mg/day | 3 | mg/day | PO, oral | Vraylar | cariprazine | PDR |
Drug Property Radar Chart
Note: Center: Q1-1.5*IQR, Edge: Q3+1.5*IQR; Q1: Quantile 1, Q3: Quantile 3, IQR: Q3-Q1