Basic Information
| Drug ID | DDPD05812 |
|
| Drug Name | Abiraterone | |
| Molecular Weight | 349.509 | |
| Molecular Formula | C24H31NO | |
| CAS Number | 154229-19-3 | |
| SMILES | [H][C@@]12CC=C(C3=CC=CN=C3)[C@@]1(C)CC[C@@]1([H])[C@@]2([H])CC=C2C[C@@H](O)CC[C@]12C | |
| External Links | ||
| DRUGBANK | DB05812 | |
| PubChem Compound | 132971 | |
| PDR | 266 | |
| Drugs.com | Drugs.com Drug Page | |
Experimental Physicochemical Property
Not Available
Pharmacokinetic/ Toxicokinetic Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Annotation | Reference |
|---|---|---|---|---|---|---|
| T Max | 2.8 | h | 1.5-4 | h | PO, oral; | DRUGBANK |
| Volume of Distribution | 19669.0 | L | 19669±13358 | L | Steady state volume of distribution; | DRUGBANK |
| Half-life | 9.5 | h | 5-14 | h | elimination half-life; | DRUGBANK |
| Eliminate Route | 88.0 | % | ~88 | % | Faeces excretion; | DRUGBANK | Eliminate Route | 5.0 | % | ~5 | % | Urinary excretion; | DRUGBANK |
| Protein Binding | 99.0 | % | >99 | % | DRUGBANK |
Maximum Dosage
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Annotation | Brand Name | Component | Reference |
|---|---|---|---|---|---|---|---|---|
| Max dose for adults | 1000.0 | mg/day | 1000 | mg/day | PO, oral | Zytiga | abiraterone acetate | PDR |
| Max dose for adults | 500.0 | mg/day | 500 | mg/day | PO, oral | Zytiga | abiraterone acetate | PDR |
| Max dose for geriatric | 1000.0 | mg/day | 1000 | mg/day | PO, oral | Zytiga | abiraterone acetate | PDR |
| Max dose for geriatric | 500.0 | mg/day | 500 | mg/day | PO, oral | Zytiga | abiraterone acetate | PDR |
Drug Property Radar Chart
Note: Center: Q1-1.5*IQR, Edge: Q3+1.5*IQR; Q1: Quantile 1, Q3: Quantile 3, IQR: Q3-Q1