| Property Name |
Property Value |
Unit |
Raw Value |
Raw Unit |
Annotation |
Reference |
| Bioavailability |
73.0 |
% |
73 |
% |
PO, oral; |
DRUGBANK |
| C Max |
584.0 |
ng/ml |
584 |
ng/ml |
PO, oral; |
DRUGBANK |
| T Max |
2.5 |
h |
2.5 |
h |
PO, oral; |
DRUGBANK |
| Clearance |
10.0 |
L/h |
10.0 |
L/h |
Plasma clearance; normal,healthy; patients; |
DRUGBANK |
Clearance |
0.14 |
L/h/kg |
2.38 |
ml/min/kg |
intravenous injection, IV; human, homo sapiens; |
Human Intravenous Pharmacokinetic Dataset |
| Volume of Distribution |
87.0 |
L |
87.0 |
L |
Average volume of distribution; |
DRUGBANK |
| Half-life |
7.5 |
h |
6-9 |
h |
elimination half-life; |
DRUGBANK |
Half-life |
6.0 |
h |
6.03 |
h |
intravenous injection, IV; human, homo sapiens; |
Human Intravenous Pharmacokinetic Dataset |
| Toxicity LD50 |
2000.0 |
mg/kg |
>2000 |
mg/kg |
PO, oral; mouse; |
DRUGBANK |
Toxicity LD50 |
2000.0 |
mg/kg |
2000.0 |
mg/kg |
PO, oral; Male, men; Rattus, Rat; |
DRUGBANK |
Toxicity LD50 |
300.0 |
mg/kg |
300.0 |
mg/kg |
PO, oral; Female, women; Rattus, Rat; |
DRUGBANK |
| Eliminate Route |
3.0 |
% |
3 |
% |
Urinary excretion; Unchanged drug; |
DRUGBANK |
Eliminate Route |
7.0 |
% |
7 |
% |
Faeces excretion; Unchanged drug; |
DRUGBANK |
| Protein Binding |
68.0 |
% |
~68 |
% |
plasma proteins; |
DRUGBANK |
