Basic Information

Drug ID DDPD05541 ...
Drug Name Brivaracetam
Molecular Weight 212.2887
Molecular Formula C11H20N2O2
CAS Number 357336-20-0
SMILES CCC[C@H]1CN([C@@H](CC)C(N)=O)C(=O)C1
External Links
DRUGBANK DB05541
PubChem Compound 9837243

Experimental Physicochemical Property

Not Available

Pharmacokinetic/ Toxicokinetic Property

Property Name Property Value Unit Raw Value Raw Unit Annotation Reference
Bioavailability 100.0 % ~100 % PO, oral; DRUGBANK
Clearance 0.0531 L/h/kg 0.7-1.07 ml/min/kg DRUGBANK
Clearance 0.0450 L/h/kg 0.75 ml/min/kg intravenous injection, IV; human, homo sapiens; Human Intravenous Pharmacokinetic Dataset
Volume of Distribution 0.50 L/kg 0.5 L/kg DRUGBANK
Volume of Distribution 0.56 L/kg 0.56 L/kg intravenous injection, IV; human, homo sapiens; Human Intravenous Pharmacokinetic Dataset
Half-life 7.5 h 7-8 h DRUGBANK
Half-life 9.0 h 8.98 h intravenous injection, IV; human, homo sapiens; Human Intravenous Pharmacokinetic Dataset
Eliminate Route 95.0 % >95 % Urinary excretion; DRUGBANK
Eliminate Route 1.0 % <1 % Faeces excretion; DRUGBANK
Protein Binding 20.0 % <20 % plasma proteins; DRUGBANK

Maximum Dosage

Not Available

Drug Property Radar Chart

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Note: Center: Q1-1.5*IQR, Edge: Q3+1.5*IQR; Q1: Quantile 1, Q3: Quantile 3, IQR: Q3-Q1