Basic Information

Drug ID DDPD05294 ...
Drug Name Vandetanib
Molecular Weight 475.354
Molecular Formula C22H24BrFN4O2
CAS Number 443913-73-3
SMILES COC1=C(OCC2CCN(C)CC2)C=C2N=CN=C(NC3=C(F)C=C(Br)C=C3)C2=C1
External Links
DRUGBANK DB05294
PubChem Compound 3081361

Experimental Physicochemical Property

Property Name Property Value Unit Raw Value Raw Unit Reference
Water Solubility 8.0 mg/L 0.008 mg/ml FDA Label

Pharmacokinetic/ Toxicokinetic Property

Property Name Property Value Unit Raw Value Raw Unit Annotation Reference
T Max 6.0 h 6 h DRUGBANK
Tss 2160.0 h 3 month DRUGBANK
Volume of Distribution 7450.0 L 7450.0 L DRUGBANK
Half-life 456.0 h 19 day DRUGBANK
Eliminate Route 44.0 % 44 % Faeces excretion; Single dose; DRUGBANK
Eliminate Route 25.0 % 25 % Urinary excretion; Single dose; DRUGBANK
Protein Binding 90.0 % ~90 % DRUGBANK

Maximum Dosage

Not Available

Drug Property Radar Chart

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Note: Center: Q1-1.5*IQR, Edge: Q3+1.5*IQR; Q1: Quantile 1, Q3: Quantile 3, IQR: Q3-Q1