Property Name |
Property Value |
Unit |
Raw Value |
Raw Unit |
Annotation |
Reference |
Bioavailability |
46.0 |
% |
46 |
% |
|
DRUGBANK |
Clearance |
13.9 |
L/h |
13.9 |
L/h |
|
DRUGBANK |
Clearance |
0.17 |
L/h/kg |
2.8 |
ml/min/kg |
intravenous injection, IV; human, homo sapiens; |
Human Intravenous Pharmacokinetic Dataset |
Volume of Distribution |
806.0 |
L |
806.0 |
L |
tumor; patients; |
DRUGBANK |
Volume of Distribution |
15.4 |
L/kg |
15.4 |
L/kg |
intravenous injection, IV; human, homo sapiens; |
Human Intravenous Pharmacokinetic Dataset |
Half-life |
44.0 |
h |
44 |
h |
|
DRUGBANK |
Half-life |
68.8 |
h |
68.8 |
h |
intravenous injection, IV; human, homo sapiens; |
Human Intravenous Pharmacokinetic Dataset |
Eliminate Route |
76.0 |
% |
76 |
% |
Faeces excretion; |
DRUGBANK |
Eliminate Route |
17.8 |
% |
17.8 |
% |
Urinary excretion; |
DRUGBANK |
Eliminate Route |
6.6 |
% |
6.6 |
% |
Faeces excretion; Unchanged drug; |
DRUGBANK |
Eliminate Route |
1.6 |
% |
1.6 |
% |
Urinary excretion; Unchanged drug; |
DRUGBANK |
Protein Binding |
95.0 |
% |
95 |
% |
plasma proteins; human, homo sapiens; |
DRUGBANK |