Basic Information
Experimental Physicochemical Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Reference |
|---|---|---|---|---|---|
| Melting Point | 245.0 | ℃ | 244-246 | ℃ | MSDS |
Pharmacokinetic/ Toxicokinetic Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Annotation | Reference |
|---|---|---|---|---|---|---|
| Bioavailability | 75.0 | % | 75 | % | Oral single dose; | DRUGBANK | Bioavailability | 75.0 | % | 75 | % | DRUGBANK |
| T Max | 3.0 | h | 3 | h | Liquid; | DRUGBANK |
| Clearance | 12.5 | L/h | 11.0-14 | L/h | DRUGBANK | |
| Volume of Distribution | 105.0 | L | 77-133 | L | Oral single dose; normal,healthy; increasing doses; | DRUGBANK |
| Half-life | 4.0 | h | ~3-5 | h | elimination half-life; | DRUGBANK |
| Eliminate Route | 77.0 | % | ~77 | % | Urinary excretion; Male, men; normal,healthy; human, homo sapiens; | DRUGBANK | Eliminate Route | 20.0 | % | ~20 | % | Faeces excretion; Male, men; normal,healthy; human, homo sapiens; | DRUGBANK |
Maximum Dosage
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Annotation | Frequency | Brand Name | Component | Reference |
|---|---|---|---|---|---|---|---|---|---|
| Max dose for adults | 123.0 | mg | 123 | mg | PO, oral | q2d | Galafold | migalastat | PDR |
| Max dose for geriatric | 123.0 | mg | 123 | mg | PO, oral | q2d | Galafold | migalastat | PDR |
Drug Property Radar Chart
Note: Center: Q1-1.5*IQR, Edge: Q3+1.5*IQR; Q1: Quantile 1, Q3: Quantile 3, IQR: Q3-Q1