| Property Name |
Property Value |
Unit |
Raw Value |
Raw Unit |
Annotation |
Reference |
| Bioavailability |
60.0 |
% |
60 |
% |
PO, oral; |
DRUGBANK |
| T Max |
1.3 |
h |
0.5-2 |
h |
Oral single dose; |
DRUGBANK |
| Tss |
72.0 |
h |
3 |
day |
Oral multiple dose; |
DRUGBANK |
| Clearance |
0.67 |
L/h/kg |
0.58 - 0.76 |
L/h/kg |
|
DRUGBANK |
Clearance |
0.50 |
L/h/kg |
8.3 |
ml/min/kg |
intravenous injection, IV; human, homo sapiens; |
Human Intravenous Pharmacokinetic Dataset |
| Volume of Distribution |
8.7 |
L/kg |
8.7 |
L/kg |
|
DRUGBANK |
Volume of Distribution |
2.5 |
L/kg |
2.5 |
L/kg |
intravenous injection, IV; human, homo sapiens; |
Human Intravenous Pharmacokinetic Dataset |
| Half-life |
7.5 |
h |
7.5 |
h |
terminal half-life; |
DRUGBANK |
Half-life |
9.0 |
h |
9 |
h |
intravenous injection, IV; human, homo sapiens; |
Human Intravenous Pharmacokinetic Dataset |
| Toxicity Lethal Dose |
100.0 |
mg/kg |
100.0 |
mg/kg |
PO, oral; Rattus, Rat; |
DRUGBANK |
Toxicity Lethal Dose |
5.1 |
mg/kg |
5.1 |
mg/kg |
PO, oral; Oral multiple dose; Rattus, Rat; |
DRUGBANK |
| Eliminate Route |
85.0 |
% |
85 |
% |
Urinary excretion; |
DRUGBANK |
Eliminate Route |
14.0 |
% |
14 |
% |
Faeces excretion; |
DRUGBANK |
Eliminate Route |
36.0 |
% |
36 |
% |
Urinary excretion; Unchanged drug; |
DRUGBANK |
Eliminate Route |
3.0 |
% |
3 |
% |
Faeces excretion; Unchanged drug; |
DRUGBANK |
| Protein Binding |
80.0 |
% |
~80 |
% |
|
DRUGBANK |
