Basic Information
| Drug ID | DDPD04938 |
|
| Drug Name | Ospemifene | |
| Molecular Weight | 378.891 | |
| Molecular Formula | C24H23ClO2 | |
| CAS Number | 128607-22-7 | |
| SMILES | OCCOC1=CC=C(C=C1)C(=C(\CCCl)C1=CC=CC=C1)\C1=CC=CC=C1 | |
| External Links | ||
| DRUGBANK | DB04938 | |
| PubChem Compound | 3036505 | |
| Drugs.com | Drugs.com Drug Page | |
Experimental Physicochemical Property
Not Available
Pharmacokinetic/ Toxicokinetic Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Annotation | Factor | Reference |
|---|---|---|---|---|---|---|---|
| AUC | 4165.0 | ng.h/ml | 4165.0 | ng.h/ml | Oral single dose; postmenopausal women; fasting; | DRUGBANK | AUC | 7521.0 | ng.h/ml | 7521.0 | ng.h/ml | Oral single dose; postmenopausal women; food; | food ↑ ; | DRUGBANK |
| C Max | 533.0 | ng/ml | 533 | ng/ml | Oral single dose; postmenopausal women; fasting; | DRUGBANK | C Max | 1198.0 | ng/ml | 1198 | ng/ml | Oral single dose; postmenopausal women; food; | food ↑ ; | DRUGBANK |
| T Max | 2.0 | h | 2(1-8) | h | Oral single dose; postmenopausal women; fasting; | DRUGBANK | T Max | 2.5 | h | 2.5(1-6) | h | Oral single dose; postmenopausal women; food; | food ↑ ; | DRUGBANK |
| Tss | 216.0 | h | 9 | day | Oral multiple dose; | DRUGBANK | |
| Clearance | 9.2 | L/h | 9.16 | L/h | Plasma clearance; | DRUGBANK | |
| Volume of Distribution | 448.0 | L | 448.0 | L | DRUGBANK | ||
| Half-life | 26.0 | h | 26 | h | terminal half-life; | DRUGBANK | |
| Eliminate Route | 75.0 | % | ~75 | % | Faeces excretion; PO, oral; | DRUGBANK | Eliminate Route | 7.0 | % | ~7 | % | Urinary excretion; PO, oral; | DRUGBANK | Eliminate Route | 0.20 | % | <0.2 | % | Urinary excretion; PO, oral; Unchanged drug; | DRUGBANK |
| Protein Binding | 99.0 | % | >99 | % | DRUGBANK |
Maximum Dosage
Not Available
Drug Property Radar Chart
Note: Center: Q1-1.5*IQR, Edge: Q3+1.5*IQR; Q1: Quantile 1, Q3: Quantile 3, IQR: Q3-Q1