Basic Information Experimental Physicochemical Property Pharmacokinetic/Toxicokinetic Property Maximum Dosage Drug Property Radar Chart

Basic Information

Drug ID DDPD04868 ...
Drug Name Nilotinib
Molecular Weight 529.5158
Molecular Formula C28H22F3N7O
CAS Number 641571-10-0
SMILES CC1=CN(C=N1)C1=CC(NC(=O)C2=CC=C(C)C(NC3=NC=CC(=N3)C3=CN=CC=C3)=C2)=CC(=C1)C(F)(F)F
External Links
DRUGBANK DB04868
PubChem Compound 644241
PDR 442

Experimental Physicochemical Property

Not Available

Pharmacokinetic/ Toxicokinetic Property

Property Name Property Value Unit Raw Value Raw Unit Annotation Reference
Half-life 15.0 h 15 h DRUGBANK

Maximum Dosage

Property Name Property Value Unit Raw Value Raw Unit Annotation Frequency Brand Name Component Reference
Max dose for children 230.0 mg/m2 230 mg/m2 bid Tasigna nilotinib PDR
Max dose for children 400.0 mg/dose 400 mg/dose Tasigna nilotinib PDR
Max dose for adolescents 230.0 mg/m2/day 230 mg/m2/day bid Tasigna nilotinib PDR
Max dose for adolescents 400.0 mg/dose 400 mg/dose Tasigna nilotinib PDR
Max dose for adults 800.0 mg/day 800 mg/day PO, oral Tasigna nilotinib PDR
Max dose for geriatric 800.0 mg/day 800 mg/day PO, oral Tasigna nilotinib PDR

Drug Property Radar Chart

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Note: Center: Q1-1.5*IQR, Edge: Q3+1.5*IQR; Q1: Quantile 1, Q3: Quantile 3, IQR: Q3-Q1