Basic Information
| Drug ID | DDPD02659 |
|
| Drug Name | Cholic Acid | |
| Molecular Weight | 408.5714 | |
| Molecular Formula | C24H40O5 | |
| CAS Number | 81-25-4 | |
| SMILES | [H][C@@](C)(CCC(O)=O)[C@@]1([H])CC[C@@]2([H])[C@]3([H])[C@]([H])(O)C[C@]4([H])C[C@]([H])(O)CC[C@]4(C)[C@@]3([H])C[C@]([H])(O)[C@]12C | |
| External Links | ||
| DRUGBANK | DB02659 | |
| T3DB | T3D4343 | |
| PubChem Compound | 221493 | |
| PDR | 3709 | |
| Drugs.com | Drugs.com Drug Page | |
Experimental Physicochemical Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Reference |
|---|---|---|---|---|---|
| Log P | 2.02 | - | 2.02 | - | RODA,A ET AL. (1990) |
| Melting Point | 198.0 | ℃ | 198 | ℃ | PhysProp |
| Water Solubility | 175.0 | mg/L | 175 | mg/L | YALKOWSKY,SH & DANNENFELSER,RM 1992) |
| pKa | 4.98 | - | 4.98 | - | SERJEANT,EP & DEMPSEY,B (1979) |
| Log S | -3.37 | - | -3.37 | - | ADME Research, USCD |
Pharmacokinetic/ Toxicokinetic Property
Not Available
Maximum Dosage
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Annotation | Brand Name | Component | Reference |
|---|---|---|---|---|---|---|---|---|
| Max dose for neonates | 15.0 | mg/kg/day | 15 | mg/kg/day | PO, oral | Cholbam | cholic acid | PDR |
| Max dose for infants | 15.0 | mg/kg/day | 15 | mg/kg/day | PO, oral | Cholbam | cholic acid | PDR |
| Max dose for infants | 17.0 | mg/kg/day | 17 | mg/kg/day | PO, oral | Cholbam | cholic acid | PDR |
| Max dose for children | 15.0 | mg/kg/day | 15 | mg/kg/day | PO, oral | Cholbam | cholic acid | PDR |
| Max dose for children | 17.0 | mg/kg/day | 17 | mg/kg/day | PO, oral | Cholbam | cholic acid | PDR |
| Max dose for adolescents | 15.0 | mg/kg/day | 15 | mg/kg/day | PO, oral | Cholbam | cholic acid | PDR |
| Max dose for adolescents | 17.0 | mg/kg/day | 17 | mg/kg/day | PO, oral | Cholbam | cholic acid | PDR |
| Max dose for adults | 15.0 | mg/kg/day | 15 | mg/kg/day | PO, oral | Cholbam | cholic acid | PDR |
| Max dose for adults | 17.0 | mg/kg/day | 17 | mg/kg/day | PO, oral | Cholbam | cholic acid | PDR |
| Max dose for geriatric | 15.0 | mg/kg/day | 15 | mg/kg/day | PO, oral | Cholbam | cholic acid | PDR |
| Max dose for geriatric | 17.0 | mg/kg/day | 17 | mg/kg/day | PO, oral | Cholbam | cholic acid | PDR |
Drug Property Radar Chart
Note: Center: Q1-1.5*IQR, Edge: Q3+1.5*IQR; Q1: Quantile 1, Q3: Quantile 3, IQR: Q3-Q1