Basic Information
Experimental Physicochemical Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Reference |
|---|---|---|---|---|---|
| Boiling Point | 325.0 | ℃ | 325 | ℃ | O'Neil, MJ. The Merxk Index. (2013) |
| Melting Point | 300.0 | ℃ | 300 | ℃ | 'MSDS' |
| Water Solubility | 65000.0 | mg/L | 65 | g/L | 'MSDS' |
| pKa | 1.5 | - | 1.5 | - | Dawson et al. Data for Biochemical Research. 3 ed. (1986) |
Pharmacokinetic/ Toxicokinetic Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Annotation | Reference |
|---|---|---|---|---|---|---|
| AUC | 29.5 | ng.h/ml | 89-3452 | mcg.min/L | PO, oral; | DRUGBANK | AUC | 200250.0 | ng.h/ml | 116-284.5 | mg.h/l | normal,healthy; | DRUGBANK |
| C Max | 8850.0 | ng/ml | 2-15.7 | mcg.min/ml | PO, oral; | DRUGBANK | C Max | 85800.0 | ng/ml | 59-112.6 | mg/L | normal,healthy; | DRUGBANK |
| T Max | 0.25 | h | 15 | min | PO, oral; | DRUGBANK | T Max | 1.8 | h | 1-2.5 | h | normal,healthy; | DRUGBANK |
| Clearance | 0.70 | L/h/kg | 11.7 | ml/min/kg | PO, oral; | DRUGBANK | Clearance | 1.1 | L/h/kg | 18.7 | ml/min/kg | PO, oral; | DRUGBANK | Clearance | 0.56 | L/h/kg | 9.4 | ml/min/kg | PO, oral; | DRUGBANK | Clearance | 24.2 | L/h | 14-34.4 | L/h | normal,healthy; | DRUGBANK |
| Volume of Distribution | 0.33 | L/kg | 299-353 | ml/kg | DRUGBANK | Volume of Distribution | 6.5 | L/kg | 4608-8374 | ml/kg | mouse; | DRUGBANK | Volume of Distribution | 30.3 | L | 19.8-40.7 | L | normal,healthy; human, homo sapiens; | DRUGBANK |
| Half-life | 1.1 | h | 0.7-1.4 | h | elimination half-life; PO, oral; normal,healthy; | DRUGBANK |
Maximum Dosage
Not Available
Drug Property Radar Chart
Note: Center: Q1-1.5*IQR, Edge: Q3+1.5*IQR; Q1: Quantile 1, Q3: Quantile 3, IQR: Q3-Q1