Basic Information
Experimental Physicochemical Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Reference |
|---|---|---|---|---|---|
| Melting Point | 146.0 | ℃ | 146 | ℃ | MSDS |
Pharmacokinetic/ Toxicokinetic Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Annotation | Factor | Reference |
|---|---|---|---|---|---|---|---|
| Bioavailability | 100.0 | % | 100 | % | intravenous injection, IV; | DRUGBANK | |
| T Max | 0.67 | h | 40 | min | PO, oral; | DRUGBANK | |
| Clearance | 0.14 | L/h/kg | 2.27±0.37 | ml/min/kg | Average clearance; normal,healthy; | DRUGBANK | Clearance | 0.0906 | L/h/kg | 1.51±0.21 | ml/min/kg | Average clearance; hypertension; | DRUGBANK | Clearance | 0.11 | L/h/kg | 1.91±0.31 | ml/min/kg | Average clearance; normal,healthy; | DRUGBANK |
| Volume of Distribution | 10.6 | L | 10.6 | L | intravenous infusion, IV in drop; | DRUGBANK | |
| Half-life | 0.24 | h | 14.3 | min | intravenous injection, IV; | normal BMI ↓ ; | DRUGBANK | Half-life | 1.3 | h | 79±2 | min | Female, women; | DRUGBANK | Half-life | 1.1 | h | 65±3 | min | Male, men; | DRUGBANK |
| Toxicity LD50 | 25800.0 | mg/kg | 25800.0 | mg/kg | PO, oral; Rattus, Rat; | DRUGBANK |
Maximum Dosage
Not Available
Drug Property Radar Chart
Note: Center: Q1-1.5*IQR, Edge: Q3+1.5*IQR; Q1: Quantile 1, Q3: Quantile 3, IQR: Q3-Q1