Basic Information Experimental Physicochemical Property Pharmacokinetic/Toxicokinetic Property Maximum Dosage Drug Property Radar Chart

Basic Information

Drug ID DDPD01580 ...
Drug Name Oxprenolol
Molecular Weight 265.348
Molecular Formula C15H23NO3
CAS Number 6452-71-7
SMILES CC(C)NCC(O)COC1=CC=CC=C1OCC=C
External Links
DRUGBANK DB01580
PubChem Compound 4631

Experimental Physicochemical Property

Property Name Property Value Unit Raw Value Raw Unit Reference
Caco-2 Permeability -4.68 - -4.68 - ADME Research, USCD
Log P 2.1 - 2.1 - HANSCH,C ET AL. (1995)

Pharmacokinetic/ Toxicokinetic Property

Property Name Property Value Unit Raw Value Raw Unit Annotation Reference
Bioavailability 45.0 % 20-70 % DRUGBANK
Clearance 0.46 L/h/kg 7.7 ml/min/kg intravenous injection, IV; human, homo sapiens; Human Intravenous Pharmacokinetic Dataset
Volume of Distribution 0.72 L/kg 0.72 L/kg intravenous injection, IV; human, homo sapiens; Human Intravenous Pharmacokinetic Dataset
Half-life 1.5 h 1-2 h DRUGBANK
Half-life 1.1 h 1.09 h intravenous injection, IV; human, homo sapiens; Human Intravenous Pharmacokinetic Dataset

Maximum Dosage

Not Available

Drug Property Radar Chart

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Note: Center: Q1-1.5*IQR, Edge: Q3+1.5*IQR; Q1: Quantile 1, Q3: Quantile 3, IQR: Q3-Q1