Basic Information Experimental Physicochemical Property Pharmacokinetic/Toxicokinetic Property Maximum Dosage Drug Property Radar Chart

Basic Information

Drug ID DDPD01577 ...
Drug Name Metamfetamine
Molecular Weight 149.2328
Molecular Formula C10H15N
CAS Number 537-46-2
SMILES CN[C@@H](C)CC1=CC=CC=C1
External Links
DRUGBANK DB01577
T3DB T3D3052
PubChem Compound 10836
PDR 1257
Drugs.com Drugs.com Drug Page

Experimental Physicochemical Property

Property Name Property Value Unit Raw Value Raw Unit Reference
Log P 2.07 - 2.07 - HANSCH,C ET AL. (1995)
pKa 9.87 - 9.87 - PERRIN,DD (1965)

Pharmacokinetic/ Toxicokinetic Property

Property Name Property Value Unit Raw Value Raw Unit Annotation Reference
T Max 4.7 h 3.13-6.3 h PO, oral; DRUGBANK
Half-life 4.5 h 4-5 h elimination half-life; DRUGBANK
Eliminate Route 45.0 % 45 % intravenous injection, IV; Unchanged drug; DRUGBANK

Maximum Dosage

Property Name Property Value Unit Raw Value Raw Unit Annotation Brand Name Component Reference
Max dose for children 22.5 mg/day 22.5 mg/day PO, oral Desoxyn methamphetamine hydrochloride PDR
Max dose for adolescents 5.0 mg 5 mg PO, oral Desoxyn methamphetamine hydrochloride PDR
Max dose for adolescents 22.5 mg/day 22.5 mg/day PO, oral Desoxyn methamphetamine hydrochloride PDR
Max dose for adults 5.0 mg 5 mg PO, oral Desoxyn methamphetamine hydrochloride PDR
Max dose for adults 22.5 mg/day 22.5 mg/day PO, oral Desoxyn methamphetamine hydrochloride PDR
Max dose for elderly 5.0 mg 5 mg PO, oral Desoxyn methamphetamine hydrochloride PDR
Max dose for elderly 22.5 mg/day 22.5 mg/day PO, oral Desoxyn methamphetamine hydrochloride PDR

Drug Property Radar Chart

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Note: Center: Q1-1.5*IQR, Edge: Q3+1.5*IQR; Q1: Quantile 1, Q3: Quantile 3, IQR: Q3-Q1