Basic Information Experimental Physicochemical Property Pharmacokinetic/Toxicokinetic Property Maximum Dosage Drug Property Radar Chart

Basic Information

Drug ID DDPD01551 ...
Drug Name Dihydrocodeine
Molecular Weight 301.3801
Molecular Formula C18H23NO3
CAS Number 125-28-0
SMILES [H][C@@]12OC3=C4C(C[C@H]5N(C)CC[C@@]14[C@@]5([H])CC[C@@H]2O)=CC=C3OC
External Links
DRUGBANK DB01551
PubChem Compound 5284543
Drugs.com Drugs.com Drug Page

Experimental Physicochemical Property

Property Name Property Value Unit Raw Value Raw Unit Reference
Melting Point 112.5 ℃ 112.5 ℃ PhysProp

Pharmacokinetic/ Toxicokinetic Property

Property Name Property Value Unit Raw Value Raw Unit Annotation Reference
AUC 3203.0 ng.h/ml 3203.0 ug.h/L PO, oral; DRUGBANK
AUC 3401.0 ng.h/ml 3401.0 ug.h/L intravenous injection, IV; DRUGBANK
Bioavailability 20.0 % 20 % PO, oral; DRUGBANK
C Max 71.8 ng/ml 71.8 ug/L intravenous injection, IV; DRUGBANK
C Max 146.0 ng/ml 146 ug/L PO, oral; DRUGBANK
Tss 1.6 h 1.6 h intravenous injection, IV; DRUGBANK
Tss 1.8 h 1.8 h PO, oral; DRUGBANK
Clearance 18.0 L/h ~300 ml/min Plasma clearance; DRUGBANK
Clearance 0.25 L/h/kg 4.21 ml/min/kg intravenous injection, IV; human, homo sapiens; Human Intravenous Pharmacokinetic Dataset
Volume of Distribution 1.1 L/kg 1.07 L/kg intravenous injection, IV; human, homo sapiens; Human Intravenous Pharmacokinetic Dataset
Half-life 4.0 h 4 h DRUGBANK
Half-life 3.4 h 3.42 h intravenous injection, IV; human, homo sapiens; Human Intravenous Pharmacokinetic Dataset

Maximum Dosage

Not Available

Drug Property Radar Chart

...

Note: Center: Q1-1.5*IQR, Edge: Q3+1.5*IQR; Q1: Quantile 1, Q3: Quantile 3, IQR: Q3-Q1