Basic Information Experimental Physicochemical Property Pharmacokinetic/Toxicokinetic Property Maximum Dosage Drug Property Radar Chart

Basic Information

Drug ID DDPD01437 ...
Drug Name Glutethimide
Molecular Weight 217.2637
Molecular Formula C13H15NO2
CAS Number 77-21-4
SMILES CCC1(CCC(=O)NC1=O)C1=CC=CC=C1
External Links
DRUGBANK DB01437
PubChem Compound 3487

Experimental Physicochemical Property

Property Name Property Value Unit Raw Value Raw Unit Reference
Log P 1.9 - 1.9 - HANSCH,C ET AL. (1995)
Melting Point 79.5 ℃ 78-81 ℃ Hoffmann, K. and Tagmann, E.; U.S. Patent 2,673,205; March 23, 1954; assigned to Ciba Pharmaceutical Products, Inc.
Water Solubility 999.0 mg/L 999 mg/L YALKOWSKY,SH & DANNENFELSER,RM 1992)
pKa 9.2 - 9.2 - SANGSTER (1994)
Log S -2.34 - -2.34 - ADME Research, USCD

Pharmacokinetic/ Toxicokinetic Property

Property Name Property Value Unit Raw Value Raw Unit Annotation Reference
Metabolic 100.0 % ~100 % Liver metabolism; DRUGBANK
Half-life 11.0 h 10-12 h DRUGBANK

Maximum Dosage

Not Available

Drug Property Radar Chart

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Note: Center: Q1-1.5*IQR, Edge: Q3+1.5*IQR; Q1: Quantile 1, Q3: Quantile 3, IQR: Q3-Q1