Basic Information
Experimental Physicochemical Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Reference |
|---|---|---|---|---|---|
| Caco-2 Permeability | -4.55 | - | -4.55 | - | ADME Research, USCD |
| Log P | 0.38 | - | 0.38 | - | HANSCH,C ET AL. (1995) |
| Boiling Point | 319.0 | ℃ | 319 | ℃ | PhysProp |
| Melting Point | 114.0 | ℃ | 114 | ℃ | PhysProp |
| Water Solubility | 51900.0 | mg/L | 51900 | mg/L | YALKOWSKY,SH & DANNENFELSER,RM 1992) |
| pKa | 1.4 | - | 1.4 | - | SANGSTER (1994) |
Pharmacokinetic/ Toxicokinetic Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Annotation | Reference |
|---|---|---|---|---|---|---|
| Clearance | 0.0384 | L/h/kg | 0.64 | ml/min/kg | intravenous injection, IV; human, homo sapiens; | Human Intravenous Pharmacokinetic Dataset |
| Volume of Distribution | 0.77 | L/kg | 0.77 | L/kg | intravenous injection, IV; human, homo sapiens; | Human Intravenous Pharmacokinetic Dataset |
| Half-life | 12.0 | h | 12 | h | intravenous injection, IV; human, homo sapiens; | Human Intravenous Pharmacokinetic Dataset |
Maximum Dosage
Not Available
Drug Property Radar Chart
Note: Center: Q1-1.5*IQR, Edge: Q3+1.5*IQR; Q1: Quantile 1, Q3: Quantile 3, IQR: Q3-Q1