Basic Information Experimental Physicochemical Property Pharmacokinetic/Toxicokinetic Property Maximum Dosage Drug Property Radar Chart

Basic Information

Drug ID DDPD01426 ...
Drug Name Ajmaline
Molecular Weight 326.4326
Molecular Formula C20H26N2O2
CAS Number 4360-12-7
SMILES CC[C@H]1[C@@H]2C[C@H]3[C@@H]4N(C)C5=CC=CC=C5[C@]44C[C@@H](C2[C@H]4O)N3[C@@H]1O
External Links
DRUGBANK DB01426
PubChem Compound 441080

Experimental Physicochemical Property

Property Name Property Value Unit Raw Value Raw Unit Reference
Log P 1.81 - 1.81 - HANSCH,C ET AL. (1995)
Melting Point 206.0 ℃ 206 ℃ PhysProp
Water Solubility 490.0 mg/L 490 mg/L YALKOWSKY,SH & DANNENFELSER,RM 1992)
Log S -2.82 - -2.82 - ADME Research, USCD

Pharmacokinetic/ Toxicokinetic Property

Property Name Property Value Unit Raw Value Raw Unit Annotation Reference
Clearance 0.59 L/h/kg 9.8 ml/min/kg intravenous injection, IV; human, homo sapiens; Human Intravenous Pharmacokinetic Dataset
Volume of Distribution 4.0 L/kg 4 L/kg intravenous injection, IV; human, homo sapiens; Human Intravenous Pharmacokinetic Dataset
Half-life 7.3 h 7.3 h intravenous injection, IV; human, homo sapiens; Human Intravenous Pharmacokinetic Dataset

Maximum Dosage

Not Available

Drug Property Radar Chart

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Note: Center: Q1-1.5*IQR, Edge: Q3+1.5*IQR; Q1: Quantile 1, Q3: Quantile 3, IQR: Q3-Q1