Basic Information Experimental Physicochemical Property Pharmacokinetic/Toxicokinetic Property Maximum Dosage Drug Property Radar Chart

Basic Information

Drug ID DDPD01403 ...
Drug Name Methotrimeprazine
Molecular Weight 328.472
Molecular Formula C19H24N2OS
CAS Number 60-99-1
SMILES COC1=CC2=C(SC3=C(C=CC=C3)N2C[C@H](C)CN(C)C)C=C1
External Links
DRUGBANK DB01403
T3DB T3D3041
PubChem Compound 72287

Experimental Physicochemical Property

Property Name Property Value Unit Raw Value Raw Unit Reference
Log P 4.68 - 4.68 - HANSCH,C ET AL. (1995)
Water Solubility 20.0 mg/L 20 mg/L YALKOWSKY,SH & DANNENFELSER,RM 1992)
pKa 9.19 - 9.19 - SANGSTER (1994)
Log S -4.22 - -4.22 - ADME Research, USCD

Pharmacokinetic/ Toxicokinetic Property

Property Name Property Value Unit Raw Value Raw Unit Annotation Reference
Bioavailability 55.0 % 50-60 % PO, oral; DRUGBANK
Half-life 20.0 h ~20 h DRUGBANK

Maximum Dosage

Not Available

Drug Property Radar Chart

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Note: Center: Q1-1.5*IQR, Edge: Q3+1.5*IQR; Q1: Quantile 1, Q3: Quantile 3, IQR: Q3-Q1