Basic Information
| Drug ID | DDPD01392 |
|
| Drug Name | Yohimbine | |
| Molecular Weight | 354.4427 | |
| Molecular Formula | C21H26N2O3 | |
| CAS Number | 146-48-5 | |
| SMILES | [H][C@@]12CC[C@H](O)[C@H](C(=O)OC)[C@@]1([H])C[C@]1([H])N(CCC3=C1NC1=CC=CC=C31)C2 | |
| External Links | ||
| DRUGBANK | DB01392 | |
| PubChem Compound | 8969 | |
| Drugs.com | Drugs.com Drug Page | |
Experimental Physicochemical Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Reference |
|---|---|---|---|---|---|
| Log P | 2.73 | - | 2.73 | - | HANSCH,C ET AL. (1995) |
| Melting Point | 241.0 | ℃ | 241 | ℃ | PhysProp |
Pharmacokinetic/ Toxicokinetic Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Annotation | Reference |
|---|---|---|---|---|---|---|
| Bioavailability | 33.0 | % | 33(7-87) | % | PO, oral; | DRUGBANK |
| Clearance | 0.88 | L/h/kg | 14.6 | ml/min/kg | intravenous injection, IV; human, homo sapiens; | Human Intravenous Pharmacokinetic Dataset |
| Volume of Distribution | 0.48 | L/kg | 0.48 | L/kg | intravenous injection, IV; human, homo sapiens; | Human Intravenous Pharmacokinetic Dataset |
| Half-life | 0.60 | h | ~36 | min | elimination half-life; | DRUGBANK | Half-life | 1.5 | h | 1.5 | h | intravenous injection, IV; human, homo sapiens; | Human Intravenous Pharmacokinetic Dataset |
Maximum Dosage
Not Available
Drug Property Radar Chart
Note: Center: Q1-1.5*IQR, Edge: Q3+1.5*IQR; Q1: Quantile 1, Q3: Quantile 3, IQR: Q3-Q1