DETAILS

Basic Information Experimental Physicochemical Property Pharmacokinetic/Toxicokinetic Property Maximum Dosage Drug Property Radar Chart

Basic Information

Drug ID	DDPD01362
Drug Name	Iohexol
Molecular Weight	821.1379
Molecular Formula	C19H26I3N3O9
CAS Number	66108-95-0
SMILES	CC(=O)N(CC(O)CO)C1=C(I)C(C(=O)NCC(O)CO)=C(I)C(C(=O)NCC(O)CO)=C1I
External Links
	DRUGBANK	DB01362
	PubChem Compound	3730

Experimental Physicochemical Property

Property Name	Property Value	Unit	Raw Value	Raw Unit	Reference
Log P	-3.05	-	-3.05	-	HANSCH,C & LEO,AJ (1985)
Melting Point	177.0	℃	174-180	℃	PhysProp

Pharmacokinetic/ Toxicokinetic Property

Property Name	Property Value	Unit	Raw Value	Raw Unit	Annotation	Reference
Clearance	6.5	L/h	109.0	ml/min	intrathecal administration; adults;	DRUGBANK
Clearance	0.12	L/h/kg	2	ml/min/kg	intravenous injection, IV; human, homo sapiens;	Human Intravenous Pharmacokinetic Dataset
Volume of Distribution	0.60	L/kg	350-849	ml/kg		DRUGBANK
Volume of Distribution	0.16	L/kg	0.16	L/kg	intravenous injection, IV; human, homo sapiens;	Human Intravenous Pharmacokinetic Dataset
Half-life	3.4	h	3.4	h		DRUGBANK
Half-life	2.0	h	~2	h	normal renal function;	DRUGBANK
Half-life	1.5	h	1.5	h	intravenous injection, IV; human, homo sapiens;	Human Intravenous Pharmacokinetic Dataset

Maximum Dosage

Not Available

Drug Property Radar Chart

Note: Center: Q1-1.5*IQR, Edge: Q3+1.5*IQR; Q1: Quantile 1, Q3: Quantile 3, IQR: Q3-Q1