Basic Information
| Drug ID | DDPD01359 |
|
| Drug Name | Penbutolol | |
| Molecular Weight | 291.4284 | |
| Molecular Formula | C18H29NO2 | |
| CAS Number | 38363-40-5 | |
| SMILES | CC(C)(C)NC[C@H](O)COC1=CC=CC=C1C1CCCC1 | |
| External Links | ||
| DRUGBANK | DB01359 | |
| PubChem Compound | 37464 | |
| Drugs.com | Drugs.com Drug Page | |
Experimental Physicochemical Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Reference |
|---|---|---|---|---|---|
| Log P | 4.15 | - | 4.15 | - | HANSCH,C ET AL. (1995) |
| Boiling Point | 438.2 | ℃ | 438.2 | ℃ | http://www.chemnet.com/cas/fr/38363-40-5/Penbutolol.html |
Pharmacokinetic/ Toxicokinetic Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Annotation | Reference |
|---|---|---|---|---|---|---|
| Absorption | 90.0 | % | >90 | % | DRUGBANK | |
| Half-life | 5.0 | h | 5 | h | DRUGBANK | Half-life | 20.0 | h | ~20 | h | normal,healthy; | DRUGBANK | Half-life | 25.0 | h | ~25 | h | normal,healthy; Elderly; | DRUGBANK | Half-life | 100.0 | h | ~100 | h | DRUGBANK |
| Protein Binding | 89.0 | % | 80-98 | % | plasma proteins; | DRUGBANK |
Maximum Dosage
Not Available
Drug Property Radar Chart
Note: Center: Q1-1.5*IQR, Edge: Q3+1.5*IQR; Q1: Quantile 1, Q3: Quantile 3, IQR: Q3-Q1