Basic Information Experimental Physicochemical Property Pharmacokinetic/Toxicokinetic Property Maximum Dosage Drug Property Radar Chart

Basic Information

Drug ID DDPD01348 ...
Drug Name Spirapril
Molecular Weight 466.614
Molecular Formula C22H30N2O5S2
CAS Number 83647-97-6
SMILES CCOC(=O)[C@H](CCC1=CC=CC=C1)N[C@@H](C)C(=O)N1CC2(C[C@H]1C(O)=O)SCCS2
External Links
DRUGBANK DB01348
PubChem Compound 5311447

Experimental Physicochemical Property

Not Available

Pharmacokinetic/ Toxicokinetic Property

Property Name Property Value Unit Raw Value Raw Unit Annotation Reference
Bioavailability 50.0 % 50 % PO, oral; DRUGBANK
Clearance 0.71 L/h/kg 11.9 ml/min/kg intravenous injection, IV; human, homo sapiens; Human Intravenous Pharmacokinetic Dataset
Volume of Distribution 0.43 L/kg 0.43 L/kg intravenous injection, IV; human, homo sapiens; Human Intravenous Pharmacokinetic Dataset
Half-life 32.5 h 30-35 h DRUGBANK
Half-life 8.6 h 8.6 h intravenous injection, IV; human, homo sapiens; Human Intravenous Pharmacokinetic Dataset

Maximum Dosage

Not Available

Drug Property Radar Chart

...

Note: Center: Q1-1.5*IQR, Edge: Q3+1.5*IQR; Q1: Quantile 1, Q3: Quantile 3, IQR: Q3-Q1